Protein Alignment Mal-A1 and Amy1a

DIOPT Version :9

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001010970.1
• Gene: Amy1a / 24203
• RGDID: 2113
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 634
• Identity: 129/634 - (20%)
• Similarity: 225/634 - (35%)
• Gaps: 222/634 - (35%)

  Fly     9 LLLAIVGFVGATEWWESGNYYQIYPRS-------FRDSDGDGIGDLNGVTEKLQ-YLKDIGFTGT 65
            |||:::|..     |...:.:..|.||       :|..|         :.::.: ||...||.|.
  Rat    15 LLLSLIGLC-----WAQYDPHTFYGRSSIVHLFEWRWVD---------IAKECERYLAPNGFGGV 65

  Fly    66 WLSPIFKSPMVDFGY--------DISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNH-- 120
            .:||..::.:|:..:        .||  |:|....|..::|..|:.:...||::|.:|.|.||
  Rat    66 QVSPPNENIVVNSPFRPWWERYQPIS--YKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMC 128

  Fly   121 --------SSTENEWFTKSVDSDPVYKDF-------YIWHDGKINNETGEREPPSNWNS-----E 165
                    |||...:|      :|..:||       :.::|||....:|..|   |:|.     :
  Rat   129 GVGAEAGQSSTCGSYF------NPNNRDFPGVPYSGFDFNDGKCKTGSGGIE---NYNDAAQVRD 184

  Fly   166 FRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVD 230
            .|.|.           |...|:::   :|....|.:.|.::|..    ||:|||:||
  Rat   185 CRLSG-----------LLDLALEK---DYVRTKVADYMNHLIDI----GVAGFRLDA-------- 223

  Fly   231 LDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVY----QW-----RELVDEFHVE 286
                                       ::|::..|:...:|.::    :|     :..:.:..::
  Rat   224 ---------------------------SKHMWPGDIKAVLDKLHNLNTKWFSEGSKPFIYQEVID 261

  Fly   287 NGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPE 351
            .||       ||.:|.|    |:|||            .:|.....:|.|:.   ::|| |....
  Rat   262 LGG-------EAVSSNE----YFGNG------------RVTEFKYGAKLGKV---LRKW-DGEKM 299

  Fly   352 GVYANWVLG--------------NHDNKRVASRFGVQRTDLINILLQTLPGHAVTYN-GEELGMT 401
            ....||..|              ||||:|   ..|...:.::......|...||.:. ....|.|
  Rat   300 AYLKNWGEGWGFMPSDRALVFVDNHDNQR---GHGAGGSSILTFWDARLYKMAVGFMLAHPYGFT 361

  Fly   402 DVWIS--W----EDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSADHTWLPVADDYK 460
            .|..|  |    |:..|.|.....|:|               :.::|....::|.|   ..:|:.
  Rat   362 RVMSSFHWPRYFENGKDVNDWVGPPNN---------------NGATKEVTINSDST---CGNDWV 408

  Fly   461 TNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGS 525
            ..:..:|:|    ::..|:.:|..:...::.....|       .:.:.|...|    .||.|
  Rat   409 CEHRWRQIR----NMVAFRNVVNGQPFANWWDNGSN-------QVAFGRGNKG----FIVFN--- 455

  Fly   526 TSKTLDLTKYYELGTQAEVITTSLSSQYIDGDV--IKSTEFVANPYVGT 572
             :...||:...:.|..|......:|...:||:.  ||       .|||:
  Rat   456 -NDDWDLSTTLQTGLPAGTYCDVISGDKVDGNCTGIK-------VYVGS 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	107/542 (20%)
		Alpha-amylase	45..404	CDD:278554	85/413 (21%)
Amy1a	NP_001010970.1	AmyAc_bac_euk_AmyA	35..426	CDD:200456	104/515 (20%)
		AmyA	56..>325	CDD:223443	75/359 (21%)
		Aamy_C	432..520	CDD:214749	18/87 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810