Protein Alignment Mal-A1 and Slc3a1

DIOPT Version :10

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_033231.2
• Gene: Slc3a1 / 20532
• MGIID: 1195264
• Length: 685
• Species: Mus musculus
• Alignment Length: 540
• Identity: 203/540 - (37%)
• Similarity: 301/540 - (55%)
• Gaps: 42/540 - (7%)

  Fly    10 LLAIVGFVGAT-----------EWWESGNYYQIYPRSFRDSDGDGIGDLNGVTEKLQYLKDIGFT 63
            ::::...:|||           :||::|..||||||||:|||.||.|||.|:.|||.|:..:...
Mouse    93 VVSVFLLIGATIAIIVISPKCLDWWQAGPIYQIYPRSFKDSDKDGNGDLKGIQEKLDYITALNIK 157

  Fly    64 GTWLSPIFKSPMVDFGYDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNHSSTENEWF 128
            ..|::..:||.:.||.|.:.||.:|.|.:|||:|||.::|...:.|:|:|:||:|||:|.::.||
Mouse   158 TLWITSFYKSSLKDFRYAVEDFKEIDPIFGTMKDFENLVAAIHDKGLKLIIDFIPNHTSDKHPWF 222

  Fly   129 TKSVDSDPVYKDFYIWHDGKINNETGEREPPSNWNSEFRYSAWEWNEVRQQYYLHQFAIQQADLN 193
            ..|......|.|:||||:  ..:..|...||:||.|.:..|:|.::|||:|.|.|||..:|.|||
Mouse   223 QSSRTRSGKYTDYYIWHN--CTHVNGVTTPPNNWLSVYGNSSWHFDEVRKQCYFHQFLKEQPDLN 285

  Fly   194 YRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEV-DLDRYNQYPDEPLTNDSVNCPDPDDHCY 257
            :|||||..|:|.:|.|||.|||.||..|||.:|.|. ||      .:|...|.| ..||...| |
Mouse   286 FRNPAVQEEIKEIITFWLSKGVDGFSFDAVKFLLEAKDL------RNEIQVNTS-QIPDTVTH-Y 342

  Fly   258 TQ--HIYTQDMPETIDMVYQWRELVDEFHVENGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIP 320
            ::  |.:|.......|:|..:|:.::::..|.|..:.:....:..|.|..|.|||......:..|
Mouse   343 SELYHDFTTTQVGMHDIVRDFRQTMNQYSREPGRYRFMGAEASAESIERTMMYYGLPFIQEADFP 407

  Fly   321 FNFDFLTSINNASKAGEYVEHIKKWMDAMPEGVYANWVLGNHDNKRVASRFGVQRTDLINILLQT 385
            || .:.|:|...|....| |.|..||:.||||.:.||:.|..:..|:.||.|.:..:.:::||.|
Mouse   408 FN-KYFTTIGTLSGHTVY-EVITSWMENMPEGKWPNWMTGGPETPRLTSRVGSEYVNAMHMLLFT 470

  Fly   386 LPGHAVTYNGEELGMTDVWI-SWEDTVDPNACNSDPDNYYARSRDPARSPYQWDASSKAGFTSAD 449
            |||..:||.|||:||.|:.: ::.::.|.....|             :||.|||.||.||||.|:
Mouse   471 LPGTPITYYGEEIGMGDISVTNFNESYDSTTLVS-------------KSPMQWDNSSNAGFTEAN 522

  Fly   450 HTWLPVADDYKTNNALQQLRAPRSHLQIFKKLVRVR-KEPSFRQGELNIQAIDDDVIIYSRQKTG 513
            |||||...||.|.|...|...|.|.|::::.|..:. .|....:|...:...|...::|:|:..|
Mouse   523 HTWLPTNSDYHTVNVDVQKTQPSSALRLYQDLSLLHATELVLSRGWFCLLRDDSHSVVYTRELDG 587

  Fly   514 SD-LYVIVLNLGSTSKTLDL 532
            .| ::::|||.|.:|..|:|
Mouse   588 IDNVFLVVLNFGESSTVLNL 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	188/479 (39%)
Slc3a1	NP_033231.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..53
		SLC3A2_N	64..123	CDD:464983	6/29 (21%)
		AmyAc_SLC3A1	115..568	CDD:200494	187/477 (39%)