Protein Alignment Mal-A1 and Amy1

DIOPT Version :9

• Sequence 1: NP_476627.3
• Gene: Mal-A1 / 35824
• FlyBaseID: FBgn0002570
• Length: 577
• Species: Drosophila melanogaster
• Sequence 2: NP_001103975.1
• Gene: Amy1 / 11722
• MGIID: 88019
• Length: 511
• Species: Mus musculus
• Alignment Length: 627
• Identity: 127/627 - (20%)
• Similarity: 216/627 - (34%)
• Gaps: 213/627 - (33%)

  Fly     9 LLLAIVGFVGATEWWESGNYYQIYPRS-------FRDSDGDGIGDLNGVTEKLQ-YLKDIGFTGT 65
            |||:::||.     |...:.:..|.|:       :|..|         :.::.: ||...||.|.
Mouse     5 LLLSLIGFC-----WAQYDPHTQYGRTAIVHLFEWRWVD---------IAKECERYLAPNGFAGV 55

  Fly    66 WLSP-----IFKSPMVDFG---YDISDFYQIHPEYGTMEDFERMIAKAKEVGIKIILDFVPNH-- 120
            .:||     :..||...:.   ..||  |:|....|..::|..|:.:...||::|.:|.|.||
Mouse    56 QVSPPNENIVVHSPSRPWWERYQPIS--YKICSRSGNEDEFRDMVNRCNNVGVRIYVDAVINHMC 118

  Fly   121 --------SSTENEWFTKSVDSDPVYKDF-------YIWHDGKINNETGEREPPSNWNS-----E 165
                    |||...:|      :|..:||       :.::|||....:|..|   |:..     :
Mouse   119 GVGAQAGQSSTCGSYF------NPNNRDFPGVPYSGFDFNDGKCRTASGGIE---NYQDAAQVRD 174

  Fly   166 FRYSAWEWNEVRQQYYLHQFAIQQADLNYRNPAVVNEMKNVIRFWLGKGVSGFRIDAVPYLFEVD 230
            .|.|.           |...|:::   :|....|.:.|.::|..    ||:|||:||
Mouse   175 CRLSG-----------LLDLALEK---DYVRTKVADYMNHLIDI----GVAGFRLDA-------- 213

  Fly   231 LDRYNQYPDEPLTNDSVNCPDPDDHCYTQHIYTQDMPETIDMVY----QW-----RELVDEFHVE 286
                                       ::|::..|:...:|.::    :|     |..:.:..::
Mouse   214 ---------------------------SKHMWPGDIKAILDKLHNLNTKWFSQGSRPFIFQEVID 251

  Fly   287 NGGDKRLLMTEAYTSFENIMTYYGNGVRNGSHIPFNFDFLTSINNASKAGEYVEHIKKWMDAMPE 351
            .||       ||.:|.|    |:|||            .:|.....:|.|:.   ::|| |....
Mouse   252 LGG-------EAVSSNE----YFGNG------------RVTEFKYGAKLGKV---MRKW-DGEKM 289

  Fly   352 GVYANWVLG--------------NHDNKRVASRFGVQRTDLINILLQTLPGHAVTYN-GEELGMT 401
            ....||..|              ||||:|   ..|.....::......|...||.:. ....|.|
Mouse   290 SYLKNWGEGWGLMPSDRALVFVDNHDNQR---GHGAGGASILTFWDARLYKMAVGFMLAHPYGFT 351

  Fly   402 DVWISWEDTVDPNACNSDPDNYYARSRDPARSPYQW------DASSKAGFTSADHTWLPVADDYK 460
            .|..|:               |:.|:....:....|      :..:|....:.|.|   ..:|:.
Mouse   352 RVMSSY---------------YWPRNFQNGKDVNDWVGPPNNNGKTKEVSINPDST---CGNDWI 398

  Fly   461 TNNALQQLRAPRSHLQIFKKLVRVRKEPSFRQGELNIQAIDDDVIIYSRQKTGSDLYVIVLNLGS 525
            ..:..:|:|    ::..|:.:|.       .|...|....|.:.:.:.|...|    .||.|...
Mouse   399 CEHRWRQIR----NMVAFRNVVN-------GQPFANWWDNDSNQVAFGRGNKG----FIVFNNDD 448

  Fly   526 TSKTLDLTKYYELGTQAEVITTSLSSQYIDGDVIKSTEFVAN 567
            .:.:..|......||..:||    |...:||:......:|.|
Mouse   449 WALSETLQTGLPAGTYCDVI----SGDKVDGNCTGIKVYVGN 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mal-A1	NP_476627.3	AmyAc_maltase	21..496	CDD:200467	105/542 (19%)
		Alpha-amylase	45..404	CDD:278554	86/413 (21%)
Amy1	NP_001103975.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	101/515 (20%)
		AmyA	46..>315	CDD:223443	76/359 (21%)
		Aamy_C	422..510	CDD:214749	17/73 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810