Protein Alignment Cyp4e2 and DIT2

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_010690.1
• Gene: DIT2 / 852011
• SGDID: S000002810
• Length: 489
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 113/518 - (21%)
• Similarity: 209/518 - (40%)
• Gaps: 103/518 - (19%)

  Fly    13 LLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNP--------------SEILDT-VFSW 62
            |.|:.:|.||......::...|.|:.:|.:         |              :|:.|. :...
Yeast     7 LCLILFLTLSYVAFAIIVPPLNFPKNIPTI---------PFYVVFLPVIFPIDQTELYDLYIRES 62

  Fly    63 WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSD-----IYQLTHPWLGLGLLTSTGS 122
            ..:||...|.|  |:..|:||:.|:||..|...:....||.     .|.....:.|..::::.|:
Yeast    63 MEKYGAVKFFF--GSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGA 125

  Fly   123 KWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHL--KTVAAGDNIFDFQEQAHYLTLDVICDT 185
            .|..:|..:|     |.||.|.:.....:.|.:..|  ..:..|.........:..:.||.|...
Yeast   126 VWRNYRNAVT-----NGLQHFDDAPIFKNAKILCTLIKNRLLEGQTSIPMGPLSQRMALDNISQV 185

  Fly   186 AMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEI 250
            |:|....|:.:..:    ||.:....|..:.|||.........:.| .|:..:..|.:..| .|:
Yeast   186 ALGFDFGALTHEKN----AFHEHLIRIKKQIFHPFFLTFPFLDVLP-IPSRKKAFKDVVSF-REL 244

  Fly   251 IAKRIEAHKSGAVSTNAGDEFTR----KKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDT 311
            :.||::            ||...    ::..|..:.|....:...::.|:|.:.:...:..||:.
Yeast   245 LVKRVQ------------DELVNNYKFEQTTFAASDLIRAHNNEIIDYKQLTDNIVIILVAGHEN 297

  Fly   312 TTSGVSFAVYLLSRHQDE-QRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSV 375
            .....:.::|||:::.:| |.||   ::||.|.::.      :.::.:..|:.|:.|..|:||.:
Yeast   298 PQLLFNSSLYLLAKYSNEWQEKL---RKEVNGITDP------KGLADLPLLNAFLFEVVRMYPPL 353

  Fly   376 -PFIGRFTEKDYVIDGDLV-PKGTTLNLGLVMLGYNEKVFKDPH----------KFRPERF--EL 426
             ..|.|.|.|...:..::| |||       |.:|||.  |...|          .|:|||:  ::
Yeast   354 STIINRCTTKTCKLGAEIVIPKG-------VYVGYNN--FGTSHDPKTWGTTADDFKPERWGSDI 409

  Fly   427 E--------KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNF--EVLPALDELVSKDG 479
            |        .........|..|.|.|:|:|.||.|::..::::::.|  .:.|..:|.::..|
Yeast   410 ETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAG 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	100/448 (22%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	102/451 (23%)