DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4e2 and CYP96A11

DIOPT Version :9

Sequence 1:	NP_001286196.1	Gene:	Cyp4e2 / 35822	FlyBaseID:	FBgn0014469	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001328516.1	Gene:	CYP96A11 / 830104	AraportID:	AT4G39500	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	564	Identity:	128/564 - (22%)
Similarity:	225/564 - (39%)	Gaps:	126/564 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLVAYLELSTFRRRRVLNKFNG--PRGLPLMGN-------AHQMGKNPSEIL---DTVFSWWHQY 66
            |::.||..:|        .:||  ||..|::|.       .|::.....|||   |..||:...
plant    27 LILHYLFKTT--------TYNGRFPRNWPVLGMLPCLLVVLHRIYDYIVEILEISDLTFSFKGP- 82

  Fly    67 GKDNFVFWIGTYSNVLVTSSKYLEFILSS--QTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRK 129
                   |......:|......:..:::|  ...|..||..::...: |.|::|:....|...||
plant    83 -------WFAGMDTLLTVDPANIHHMMNSNFSNYIKGSDFKEVFDVF-GDGIITTDSELWKNLRK 139

  Fly   130 MITPAFHFNILQDFHEVMNENSTK--FIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSIN 192
            ......|....|.|......:..|  .:..|...|......|.|:.....|.|.|.     :.|.
plant   140 SYQEMLHHQAFQSFSLSTTRSKLKDGLVPLLNHFAEEGTTVDLQDVLGRFTFDTIL-----ILIT 199

  Fly   193 AMENRSSSIVQAFKDMCYNINMRA----FHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAK 253
            ..:.||.||.....::...:::..    |..:|            |.:...|:....|.:|  .|
plant   200 GSDPRSLSIEMHEDELAKALDVVGEGIFFRHVK------------PKFLWKLQNWMGFGHE--KK 250

  Fly   254 RIEAHK------SGAVSTNAGDEFTRKKMAFL-----DTLLSS--TIDG------RPLNSKELYE 299
            .|||:.      :..:|...|:....::.:.:     :.||||  .:|.      .|.:.|.|.:
plant   251 MIEANATFDRVCAKYISDKRGEIIRSQRFSDISYGEPEDLLSSFMKLDTTKYNLLNPSDDKFLRD 315

  Fly   300 EVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQE-ISQMKYLDL 363
            .:..|:..|.|||.|.:::..:|||    |..::..:.|:.:.|:...::...|| :.::.||..
plant   316 TILAFILAGRDTTASALTWFFWLLS----ENAQVVSKIRQEIINTNPSKNGNGQENLDKLVYLHG 376

  Fly   364 FIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKG------TTLNLGLVMLGYNEKVF-KDPHKFRP 421
            .:.||.|:||.|.| ||.:.    |..|::|.|      :.:.:.|..||....|: .|..:|:|
plant   377 ALCEAMRLYPPVSF-GRKSP----IKSDVLPSGHKVQANSKIIICLYALGRMRAVWGDDALEFKP 436

  Fly   422 ERFELEKPG-----PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI 481
            ||:..:|..     .|:::.|::|||.|:|:..|:.::|.|..:|:.|:|:      .|.|.
plant   437 ERWVSDKGSLRHEPSFKFLSFNSGPRTCLGKHLAMTQMKMVAVEILHNYEI------KVIKG--- 492

  Fly   482 STTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525
                              .|..|:|..:|::|  :||.|.:.:|
plant   493 ------------------QKIKPVLGFILSMK--HGLRITITKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	112/485 (23%)
CYP96A11	NP_001328516.1	p450	10..516	CDD:386267	127/562 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H111093
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920