DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e2 and CYP96A2

DIOPT Version :9

Sequence 1:	NP_001286196.1	Gene:	Cyp4e2 / 35822	FlyBaseID:	FBgn0014469	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_194944.1	Gene:	CYP96A2 / 829349	AraportID:	AT4G32170	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	137/538 - (25%)
Similarity:	220/538 - (40%)	Gaps:	126/538 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 WFVLYIFLALPLLL----------VAYLELS--TFRRRRVLNKFNGPR--GLPLMGNAHQMGKNP 52
            |.||.:   ||.:|          |..||.|  ||       .|.|||  |:.::     :..:|
plant    35 WPVLRM---LPAMLKALHRIYDYSVKILETSDLTF-------PFKGPRFTGMDML-----LTVDP 84

  Fly    53 SEILDTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLL 117
            :.|        |.....||       ||.:    |..||          .|::.:    ||...:
plant    85 ANI--------HHIMSSNF-------SNYI----KGPEF----------QDVFDV----LGDSFI 116

  Fly   118 TSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKH-----LKTVAAGDNIFDFQEQAHYL 177
            |:....|...||......|   .|:|........|..:|:     |...|......|.|......
plant   117 TTDSELWKNMRKSYQAMLH---SQEFQRFSMSTMTSKLKYGLVPLLNHFAEEGTTLDLQSVFGRF 178

  Fly   178 TLDVICDTAMGVSINAMENRSSSI-------VQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPA 235
            |.|.|.     :.:...:.||.||       .:|..|:...|..|.|.|    ..|::| .::..
plant   179 TFDTIF-----ILVTGSDPRSLSIEMPEDEFAKALDDVGEGILYRHFKP----RFLWKL-QNWIG 233

  Fly   236 YSRTLK-TLQDFTNE------IIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLN 293
            :.:..| |..:.|.:      |.|||.|..:|...| |.|.:........|||.....::  |.:
plant   234 FGQEKKLTEANATFDRVCAKYISAKREEIKRSQGTS-NGGSQDLLTSFIKLDTTKYKLLN--PSD 295

  Fly   294 SKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQE-ISQ 357
            .|.|.:.:..|:..|.|||.:.:|:..:|||.:.....|:   .:|:..|::|.|....|| :.:
plant   296 DKFLRDNILAFILAGRDTTATALSWFFWLLSENPHVVAKI---HQEININTDLSRTGNSQENVDK 357

  Fly   358 MKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKG------TTLNLGLVMLGYNEKVF-KD 415
            :.||...:.||.|:||.|.| ||.:.    |..|::|.|      :.:.:.|..||....|: :|
plant   358 LVYLHGALCEAMRLYPPVSF-GRKSP----IKSDVLPSGHKVDANSKIIICLYALGRMRAVWGED 417

  Fly   416 PHKFRPERFELEKPG-----PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE--------V 467
            ..:|:|||:..|..|     .|:::.|:||||.|:|:..|:.::|.|..:|:||::        :
plant   418 ASQFKPERWISENGGIKHEPSFKFLSFNAGPRTCLGKHLAMTQMKIVAVEILRNYDIKVLQGQKI 482

  Fly   468 LPALDELVSKDGYISTTI 485
            :|||..::|....:..|:
plant   483 VPALGFILSMKHGLQITV 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	119/475 (25%)
CYP96A2	NP_194944.1	p450	1..503	CDD:416425	137/538 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H111093
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010