DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e2 and LUT1

DIOPT Version :9

Sequence 1:	NP_001286196.1	Gene:	Cyp4e2 / 35822	FlyBaseID:	FBgn0014469	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_190881.2	Gene:	LUT1 / 824479	AraportID:	AT3G53130	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	115/530 - (21%)
Similarity:	236/530 - (44%)	Gaps:	77/530 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LSTFRRRRVLNKFNGPRGLP-----------LMGNAHQMGKNPSEILDTVFSWWHQYGKDNFVFW 74
            |:|..|.....| |...|:|           |:|.|         :...::.|.::||.   ::.
plant    62 LTTLTRTLSSGK-NDESGIPIANAKLDDVADLLGGA---------LFLPLYKWMNEYGP---IYR 113

  Fly    75 I--GTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHF 137
            :  |..:.|:|:.....:.:|.:.....|..:.:::....|.|...:.|..|...|:.:.|:.|.
plant   114 LAAGPRNFVIVSDPAIAKHVLRNYPKYAKGLVAEVSEFLFGSGFAIAEGPLWTARRRAVVPSLHR 178

  Fly   138 NILQDFHE-VMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAMENRSSSI 201
            ..|....| |..:.:.:.::.|:..|...:..:.:.:...:|||||..:....:.::: ...|.:
plant   179 RYLSVIVERVFCKCAERLVEKLQPYAEDGSAVNMEAKFSQMTLDVIGLSLFNYNFDSL-TTDSPV 242

  Fly   202 VQAFKDMCYNINMRA--FHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVS 264
            ::|.........:|:  ..|..:.:.|.::.|......:.:..:::...::|||..|..:.....
plant   243 IEAVYTALKEAELRSTDLLPYWKIDALCKIVPRQVKAEKAVTLIRETVEDLIAKCKEIVEREGER 307

  Fly   265 TNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDE 329
            .|..:.......:.|..||:|.   ..::|.:|.:::.:.:..||:||.|.:::.:||||::...
plant   308 INDEEYVNDADPSILRFLLASR---EEVSSVQLRDDLLSMLVAGHETTGSVLTWTLYLLSKNSSA 369

  Fly   330 QRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDL-V 393
            .||..:|...|:.    ||:..|::|.::||:...|.|:.|:||..|.:.|..:...::.|:. |
plant   370 LRKAQEEVDRVLE----GRNPAFEDIKELKYITRCINESMRLYPHPPVLIRRAQVPDILPGNYKV 430

  Fly   394 PKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGP------FEYVPFSAGPRNCIGQKFALL 452
            ..|..:.:.:..:..:.:|::...:|.||||:::...|      |:::|||.|||.|:|.:|||:
plant   431 NTGQDIMISVYNIHRSSEVWEKAEEFLPERFDIDGAIPNETNTDFKFIPFSGGPRKCVGDQFALM 495

  Fly   453 EIKTVVSKIIR--NFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSE 515
            |....::..::  |.|::|        |..||.|.|                       .|:.:.
plant   496 EAIVALAVFLQRLNVELVP--------DQTISMTTG-----------------------ATIHTT 529

  Fly   516 NGLYIRLKER 525
            ||||:::.:|
plant   530 NGLYMKVSQR 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	98/458 (21%)
LUT1	NP_190881.2	PLN02936	56..539	CDD:178524	114/528 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920