Protein Alignment Cyp4e2 and cyp4v2.2

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001072667.1
• Gene: cyp4v2.2 / 780124
• XenbaseID: XB-GENE-977085
• Length: 523
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 197/540 - (36%)
• Similarity: 288/540 - (53%)
• Gaps: 50/540 - (9%)

  Fly     5 LYIFLALPLLLVAYLELSTF-------RRRRVLNKFNGP-RGLPLMGNAHQMGKNPSEILDTVFS 61
            |.:::|..::|:..|.||..       |:||:|....|| ...||:|:|..:..|..:....:..
 Frog     9 LLVWVAAAVVLLTLLALSILPALQDYVRKRRILKPIPGPGPNYPLIGDALFLKNNGGDFFLQICE 73

  Fly    62 WWHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWH 125
            :...|.....: .||||...::|..:..:|.:|||...:.|:.:|:..|||||.|||||||.||.
 Frog    74 YTESYRLQPLLKVWIGTIPFIVVYHADTVEPVLSSSKHMDKAFLYKFLHPWLGKGLLTSTGEKWR 138

  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190
            ..||||||.|||.||.:|.|||||.|...::.|:|...|:: ||.........||:|.:||||..
 Frog   139 SRRKMITPTFHFAILSEFLEVMNEQSKILVEKLQTHVDGES-FDCFMDVTLCALDIISETAMGRK 202

  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI 255
            |.|..||.|..|||...|...|..|...|....:.||....|...:.:.||.|..||::.|.:|.
 Frog   203 IQAQSNRDSEYVQAIYKMSDIIQRRQKMPWLWLDFLYAHLRDGKEHDKNLKILHSFTDKAILERA 267

  Fly   256 E------AHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTT 313
            |      ..|.....::...:..:|:.||||.||.:|.| |..::..::.|||.||||||||||.
 Frog   268 EELKKMGEQKKEHCDSDPESDKPKKRSAFLDMLLMATDDAGNKMSYMDIREEVDTFMFEGHDTTA 332

  Fly   314 SGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFI 378
            :.::::::||..|.:.||::.||..||.|.|:  |..|..::.:::||:..|||:.|:|||||..
 Frog   333 AALNWSLFLLGSHPEAQRQVHKELDEVFGKSD--RPVTMDDLKKLRYLEAVIKESLRIYPSVPLF 395

  Fly   379 GRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP---GPFEYVPFSAG 440
            ||...:|..|.|..||||..:.:....|..:.:.|.:|.:||||||..|..   .|:.|:|||||
 Frog   396 GRTVTEDCSIRGFHVPKGVNVVIIPYALHRDPEYFPEPEEFRPERFFPENASGRNPYAYIPFSAG 460

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPI 505
            .||||||:|||:|.|.|:|.|:||:.|                     :|.:|:.       :..
 Frog   461 LRNCIGQRFALMEEKVVLSSILRNYWV---------------------EASQKRE-------ELC 497

  Fly   506 LSAVLTLKSENGLYIRLKER 525
            |...|.|:.::|::|:||.|
 Frog   498 LLGELILRPQDGMWIKLKNR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	177/445 (40%)
cyp4v2.2	NP_001072667.1	p450	45..509	CDD:365848	182/494 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010