Protein Alignment Cyp4e2 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 503
• Identity: 115/503 - (22%)
• Similarity: 191/503 - (37%)
• Gaps: 101/503 - (20%)

  Fly     9 LALPLLLVAYLELSTFRRRRVLNKF------NGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQYG 67
            :::.|||....:|...|.....:|.      .|..|.||:|.              .|.|..| |
 Frog    20 VSVALLLAVSQQLWQLRWAATRDKSCKLPIPKGSMGFPLVGE--------------TFHWILQ-G 69

  Fly    68 KDNFVFWIGTYSNVL-----------VTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTG 121
            .|........|.||.           ||.::.:..||..:..:..::..:.|...||...|.::.
 Frog    70 SDFQSSRREKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNSLANSI 134

  Fly   122 SKWHKH-RKMITPAFHFN-----------ILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQA 174
            ...|:| ||:.:..|...           ::||...|.:.|....           |::.   :|
 Frog   135 GDIHRHKRKVFSKIFSHEALESYLPKIQLVIQDTLRVWSSNPESI-----------NVYC---EA 185

  Fly   175 HYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYP--AYS 237
            ..||..:.....:|..::  :...|.:.|.|:....|:              :.|..|.|  .|.
 Frog   186 QKLTFRMAIRVLLGFRLS--DEELSQLFQVFQQFVENV--------------FSLPVDVPFSGYR 234

  Fly   238 RTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEV 301
            |.::     ..|::.|.:|......:....|.::...    ||.|:.|..: |:.|..:||.:..
 Frog   235 RGIR-----AREMLLKSLEKAIQEKLQNTQGKDYADA----LDILIESGKEHGKELTMQELKDGT 290

  Fly   302 STFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDAT------FQEISQMKY 360
            ...:|..:.||.|..:..:..|.:|.....||   :.|:.|||.|.....      .:.||.:.|
 Frog   291 LELIFAAYATTASASTSLIMQLLKHPSVLEKL---REELRGNSILHNGCVCEGALRVETISSLHY 352

  Fly   361 LDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF- 424
            ||..|||..|::..|....|...:.:.:||..:|||.::...:........||||...|.|:||
 Frog   353 LDCVIKEILRLFSPVSGGYRTVLQTFELDGFQIPKGWSVLYSIRDTHDTAPVFKDVDVFDPDRFG 417

  Fly   425 ---ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKI--IRNFEV 467
               ..:|.|.|.|:||..|.|||:|:..|.|.:|.:..::  :..||:
 Frog   418 QDRTEDKDGRFHYLPFGGGVRNCLGKHLAKLFLKVLAIELASMSRFEL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	100/438 (23%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	105/463 (23%)