Protein Alignment Cyp4e2 and Cyp4f37

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 473
• Identity: 134/473 - (28%)
• Similarity: 239/473 - (50%)
• Gaps: 57/473 - (12%)

  Fly    68 KDNFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSD--IYQLTHPWLGLGLLTSTGSKWHKHRK 129
            :|..:.|:|....|| :....::..:|.:..|:...|  .:....||||.||..::|.||.:||:
Mouse    85 RDVHLCWLGPVIPVLRIVDPAFVAPLLLASALVAPKDTTFHTFVKPWLGDGLFLNSGDKWSRHRR 149

  Fly   130 MITPAFHFNILQDFHEVMNEN----STKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190
            ::||||||:||:.:.::.|::    ..|: |||.  :.|....:..|....:|||.:.....|..
Mouse   150 LLTPAFHFDILKPYVKIFNQSVNIMHAKW-KHLS--SEGSARLEMFEHISLMTLDSLQKCLFGFD 211

  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI 255
            .|..|: .|..:.|..::...:..|:.......:.||....|...:.:....:.:||:.:|.:|
Mouse   212 SNCQES-PSEYISAILELSSLVIKRSHQLFLFVDFLYYHTADGRRFRKACDLVHNFTDAVIRER- 274

  Fly   256 EAHKSGAVSTNAGDEFTRKK-----MAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTTS 314
             .|   .:|:...|||.:.|     :.|:|.||.:..: |:.|:.:::..|..||||.|||||.|
Mouse   275 -RH---TLSSQNHDEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTAS 335

  Fly   315 GVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIG 379
            .:|:.:|.|:||.:.|.:..:|.:|::...| .::..:.:::|:.:|.:.|||:.|::|.|..:.
Mouse   336 ALSWILYNLARHPEYQERCRQEVQELLRGRE-PQEIEWDDLAQLPFLTMCIKESLRLHPPVIDLL 399

  Fly   380 RFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELE---KPGPFEYVPFSAG 440
            |...:|.|: ||.::|||....:.:..:.:|..|:.||..:.|.||:.|   |..|..::|||||
Mouse   400 RRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVYDPFRFDPENAHKRPPLAFIPFSAG 464

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPI 505
            |||||||.||:.|:...::..:..|.:                   |||.:..:|.|
Mouse   465 PRNCIGQTFAMNEMMVALALTLLRFRI-------------------LPDDKEPRRKP-------- 502

  Fly   506 LSAVLTLKSENGLYIRLK 523
               .:.|::|.||::|::
Mouse   503 ---EIILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	124/417 (30%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	133/469 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845188
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.640