Protein Alignment Cyp4e2 and LOC5667940

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_001688205.2
• Gene: LOC5667940 / 5667940
• VectorBaseID: AGAMI1_005329
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 552
• Identity: 125/552 - (22%)
• Similarity: 230/552 - (41%)
• Gaps: 97/552 - (17%)

  Fly     5 LYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLP------LMGNAHQMGKNPSEILDTVFSWW 63
            ||:.:::..|||.::     ||||   .:...|.:|      |:||..  |.....:.|.....:
Mosquito     7 LYLCVSVVCLLVLWI-----RRRR---NYWSTRNVPTIPGHFLLGNFE--GLRRQSVADVSNELY 61

  Fly    64 HQYG-KDNFV-FWIGTYSNVLVTSSKYLEFILSSQ-TLITKSDIYQLTH-PWLGLGLLTSTGSKW 124
            .|.. ::.|. ..|.....:::|....::.:|... ...|...:|.... ..|...|....|:||
Mosquito    62 RQVDRRERFCGLSIMLQPTLMITDLDLIKSVLIKDFAHFTDHGVYHNERVDVLSCHLFCLEGAKW 126

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGV 189
            ...|..::|||....::....::.:.:..|...|:|...|....|.::....:.:|.|...|.|:
Mosquito   127 KSIRSKLSPAFTTGRIRAMFPILRQVADNFAHFLRTEVDGKAELDMKDCCARMMIDNIGGCAFGI 191

  Fly   190 SINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTL-------KTLQDFT 247
            ..|:.....|    ||:    ......|...:.::::..|...|||....|       :.::.||
Mosquito   192 ECNSFHEPDS----AFR----RTGELVFDKPRHSQVVSSLLRLYPALGHLLGLKVNHDEVVEFFT 248

  Fly   248 ---NEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLS--STIDGRPLNSKELYEEVSTFMFE 307
               ...:|.|:           :.|..|.|:...:|.:|.  :..:|..|:..||..:...|...
Mosquito   249 GMMRRTVAMRV-----------SSDTATPKRNDLIDMMLQLRAASNGSALSMDELMAQAFGFFLA 302

  Fly   308 GHDTTTSGVSFAVY--LLSRHQDEQRKLFKEQ--REVMGNSELGRDATFQEISQMKYLDLFIKEA 368
            |::|::|.|:|.:|  .|:.|..|:.::...|  |:..|       .|::.:.:|:|||..|.|.
Mosquito   303 GYETSSSNVTFCLYELALNEHCQERARVCVRQALRKHGG-------LTYEALGEMEYLDRCINET 360

  Fly   369 QRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGP 431
            .|.||.:|.:.|.|.|.|.|.|.  ::|....::|.:..:..:|:.:.||.:|.|:||..::...
Mosquito   361 LRKYPPLPLLPRLTSKAYRIPGSDVILPAKMRIHLPVYAIQRDERYYPDPDRFDPDRFAPDRVAE 425

  Fly   432 ---FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERK 493
               ..::||..|||.||||:..:|:.:..::.::.||.|.|.
Mosquito   426 RHFSAFLPFGEGPRICIGQRLGVLQSRIGLATVLANFRVRPG----------------------- 467

  Fly   494 KRDPYRHKYDPILSA--VLTLKSENGLYIRLK 523
            .|.|.     |::.|  .:||:|...:|::::
Mosquito   468 PRTPI-----PLVFAKDAVTLQSAGEVYLQVE 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	107/477 (22%)
LOC5667940	XP_001688205.2	None