Protein Alignment Cyp4e2 and cyp4v7

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001073465.1
• Gene: cyp4v7 / 562008
• ZFINID: ZDB-GENE-061103-88
• Length: 510
• Species: Danio rerio
• Alignment Length: 556
• Identity: 190/556 - (34%)
• Similarity: 290/556 - (52%)
• Gaps: 85/556 - (15%)

  Fly     3 FVLYI----FLALPLLLV---AYLELSTFRRRRVLNKFNGPRGL-------PLMGNAHQMGKNPS 53
            |.|||    |.|:.|||:   ||..|..:     :.|:|..|.:       |::|||.|...|..
Zfish     5 FGLYILGILFTAVLLLLLASTAYNPLKNY-----IGKWNEMRPIPGMAGAYPIIGNALQFKTNAG 64

  Fly    54 EILDTVFSWWHQ-----YGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLG 113
            :..:.:....::     ..|    .|:|....:::..::.:|.:||:...:.||..|:..|||||
Zfish    65 DFFNQIIEGTNENRHLPLAK----VWVGPVPFLILYHAENIEVVLSNSRHLDKSYSYRFLHPWLG 125

  Fly   114 LGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGD--NIFDFQEQAHY 176
            .|||||||.||...|||:||.|||:||.||.|||||.:...|:.::.:..|:  |.|:|   ...
Zfish   126 TGLLTSTGEKWRNRRKMLTPTFHFSILSDFLEVMNEQTDILIQKMQKLEDGEPFNCFNF---ITL 187

  Fly   177 LTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLK 241
            ..||:||:||||..|.|..|..|..||:...|...|..|...|....:.:|....:...:::.||
Zfish   188 CALDIICETAMGKKIYAQSNADSEYVQSVYKMSDIITKRQRAPWLWPDWIYNKLKEGKEHAKRLK 252

  Fly   242 TLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID-GRPLNSKELYEEVSTFM 305
            .|..||..:|.:|.|...|...|.:  |:..||:.||||.||.:|.: |:.|:.:::.|||.|||
Zfish   253 ILHSFTANVIRERAEFMSSEPDSDS--DQGERKRQAFLDMLLKTTYENGQKLSHEDIQEEVDTFM 315

  Fly   306 FEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQR 370
            |||||||.:.:::|::|:..|.:.|:.:..|.:||.|:||  |....:::.:::||:..|||:.|
Zfish   316 FEGHDTTAASMNWALHLIGSHPEVQKAVQAELQEVFGSSE--RHVGVEDLKKLRYLECVIKESLR 378

  Fly   371 VYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP---GPF 432
            ::||||...|...:...|:|..||||....:....|..:.:.|.:|.:|:||||..|..   .|:
Zfish   379 IFPSVPLFARSICEACHINGFKVPKGVNAVIIPYALHRDPRYFPEPEEFQPERFMPENSKGRHPY 443

  Fly   433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV--------LPALDELVSKDGYISTTIGLPD 489
            .|:||||||||||||:||::|.|.|::.|:|:|:|        |..|.||:
Zfish   444 AYIPFSAGPRNCIGQRFAMMEEKVVLATILRHFDVEACQSREELRPLGELI-------------- 494

  Fly   490 AERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525
                                  |:.|.|::|:|:.|
Zfish   495 ----------------------LRPEKGIWIKLQRR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	166/459 (36%)
cyp4v7	NP_001073465.1	p450	44..505	CDD:278495	173/507 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589848
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.850