Protein Alignment Cyp4e2 and Cyp6a17

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001286433.1
• Gene: Cyp6a17 / 45556
• FlyBaseID: FBgn0015714
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 129/552 - (23%)
• Similarity: 239/552 - (43%)
• Gaps: 90/552 - (16%)

  Fly     9 LALPLLLVAYLELSTFRRRRVLNKFNGPRGL------PLMGNAHQMGKNPSEILDTVFSWWHQYG 67
            :.|..|:|..|.|..|..|| .:.:...||:      ||.||.... .|...|.:....::.:|.
  Fly     1 MLLLALIVVILSLLVFAARR-RHGYWQRRGIPHDEVHPLFGNIKDW-PNKRHIAEIFRDYYFKYK 63

  Fly    68 KDNFVFWIGTY----SNVLVTSSKYLEFIL--SSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHK 126
            ..::.| .|.:    ...:||..:.|:.:|  .......:...|......|...|.:..|.||..
  Fly    64 NSDYPF-AGFFFFFTRTAVVTDMELLKRVLIKDFNHFENRGVFYNEIDDPLSATLFSIEGQKWRH 127

  Fly   127 HRKMITPAFHFNILQDFHEV---MNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMG 188
            .|..:||.|....:::...:   :.|...|..:. ||.|....:.:..:.....|.|||.:.|.|
  Fly   128 LRHKLTPTFTSGKMKNMFPIVVKVGEEMDKVFRS-KTAADRGQVLEVVDLVARYTADVIGNCAFG 191

  Fly   189 VSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLK------TLQDFT 247
            ::.|::.:..:..|        :|..||....:...:|......:|..||.|:      ..:||.
  Fly   192 LNCNSLYDPKAEFV--------SIGKRAITEHRYGNMLDIFLFGFPKLSRRLRLKLNIQEAEDFY 248

  Fly   248 NEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLL--------SSTIDGRPLNSKELYEEVSTF 304
            .:|:.:.|:..    :.|.      .|:..|:|:|:        .::.||...|  ||..:...|
  Fly   249 TKIVRETIDYR----LRTK------EKRNDFMDSLIEMYKNEQSGNSEDGLTFN--ELLAQAFIF 301

  Fly   305 MFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGN--SELGRDATFQEISQMKYLDLFIKE 367
            ...|.:|:::.:.||:|.|:|:||.|.||    ||.:||  .:..::.|::.|.:||||:..:.|
  Fly   302 FVAGFETSSTTMGFALYELARNQDVQDKL----REEIGNVFGKHNKEFTYEGIKEMKYLEQVVME 362

  Fly   368 AQRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELE 427
            ..|.||.:..:.|.|:.|:..:..  .:.|||.:.:..:.:.|:..::.:|..|:||||   |:.
  Fly   363 TLRKYPVLAHLTRMTDTDFSPEDPKYFIAKGTIVVIPALGIHYDPDIYPEPEIFKPERFTDEEIA 427

  Fly   428 KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAER 492
            ......::||..|||||||.:|.:::....::.:||.::.      .||.:..|...|
  Fly   428 ARPSCTWLPFGEGPRNCIGLRFGMMQTCVGLAYLIRGYKF------SVSPETQIPMKI------- 479

  Fly   493 KKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524
                        ::..:| :.:|||:::::::
  Fly   480 ------------VVKNIL-ISAENGIHLKVEK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	113/469 (24%)
Cyp6a17	NP_001286433.1	p450	36..478	CDD:278495	114/474 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810