Protein Alignment Cyp4e2 and dib

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_524810.2
• Gene: dib / 45282
• FlyBaseID: FBgn0000449
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 121/529 - (22%)
• Similarity: 227/529 - (42%)
• Gaps: 103/529 - (19%)

  Fly    14 LLVAYLELSTFRRRRVLNK----FNGPRGLPLMGNAHQ----MGKNPSEILDTVFSW--WHQYGK 68
            :|...|::|...|:....|    ..||||...|||.:.    :|.         :||  .||.|:
  Fly     1 MLTKLLKISCTSRQCTFAKPYQAIPGPRGPFGMGNLYNYLPGIGS---------YSWLRLHQAGQ 56

  Fly    69 DNF----------------VFWIGTYSNVLVTSS-----KYLEFILSSQTLITKSDIYQLTHPWL 112
            |.:                :.|:....::.:..:     :....:..:|...::.|:|:.|
  Fly    57 DKYEKYGAIVRETIVPGQDIVWLYDPKDIALLLNERDCPQRRSHLALAQYRKSRPDVYKTT---- 117

  Fly   113 GLGLLTSTGSKWHKHRKMI-----TPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQE 172
              |||.:.|.:|.:.|..:     .|....|.::....|..|    ||:.|:....|..| |...
  Fly   118 --GLLPTNGPEWWRIRAQVQKELSAPKSVRNFVRQVDGVTKE----FIRFLQESRNGGAI-DMLP 175

  Fly   173 QAHYLTLDVICDTAMGV---SINAME----NRSSSIVQAFK--DMCYNINMRAFHPLKRNELLYR 228
            :...|.|::.|....|.   |..|.|    :||:.::.|.:  :.|       ..|..:...|:|
  Fly   176 KLTRLNLELTCLLTFGARLQSFTAQEQDPRSRSTRLMDAAETTNSC-------ILPTDQGLQLWR 233

  Fly   229 LAPDYPAYSRTLKTLQDFTNEIIAKRIEAH-KSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPL 292
            .. :.|:: |.|...|.:...:..:.:|.: ::|:|.:               :|:|:.:....|
  Fly   234 FL-ETPSF-RKLSQAQSYMESVALELVEENVRNGSVGS---------------SLISAYVKNPEL 281

  Fly   293 NSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVM--GNSELGRDATFQEI 355
            :..::....:..:..|.|||:...:|.:|.::|:.:.|:||.:|.|.|:  ...||..||...:|
  Fly   282 DRSDVVGTAADLLLAGIDTTSYASAFLLYHIARNPEVQQKLHEEARRVLPSAKDELSMDALRTDI 346

  Fly   356 SQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFR 420
            :   |....:||:.|:.|....:||...:|.:..|..||||||:....::....|:.|:||.:|:
  Fly   347 T---YTRAVLKESLRLNPIAVGVGRILNQDAIFSGYFVPKGTTVVTQNMVACRLEQHFQDPLRFQ 408

  Fly   421 PERFELEKP--GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVL--PALDELVSKDGYI 481
            |:|:...:.  .|:..:||..|.|.||.::.|...:..::.:::|.:|::  .:.||:    |..
  Fly   409 PDRWLQHRSALNPYLVLPFGHGMRACIARRLAEQNMHILLLRLLREYELIWSGSDDEM----GVK 469

  Fly   482 STTIGLPDA 490
            :..|..|||
  Fly   470 TLLINKPDA 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	103/465 (22%)
dib	NP_524810.2	CYP24A1-like	59..480	CDD:410677	102/462 (22%)