Protein Alignment Cyp4e2 and Cyp4c3

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_524598.1
• Gene: Cyp4c3 / 43663
• FlyBaseID: FBgn0015032
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 504
• Identity: 182/504 - (36%)
• Similarity: 276/504 - (54%)
• Gaps: 39/504 - (7%)

  Fly     7 IFL--ALPLLLVAYLELSTFRRRRV---LNKFNGPRGLPLMGNAHQMGKNPSEILDTVFS----W 62
            :||  ::.:.||.|.:    ||.|:   :.|..||..:|.:|||.:|..:..|:.:.|..    |
  Fly    31 VFLLGSILIFLVVYNK----RRSRLVKYIEKIPGPAAMPFLGNAIEMNVDHDELFNRVIGMQKLW 91

  Fly    63 WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKH 127
            ..:.|.:.  .|.||...||:...:.:|.||:||..:.||..|...|||||.||||||..|||..
  Fly    92 GTRIGINR--VWQGTAPRVLLFEPETVEPILNSQKFVNKSHDYDYLHPWLGEGLLTSTDRKWHSR 154

  Fly   128 RKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSIN 192
            ||::||||||.||.||.:|.||.|....:.| .|..|...|:........|||::|:||||..|.
  Fly   155 RKILTPAFHFKILDDFIDVFNEQSAVLARKL-AVEVGSEAFNLFPYVTLCTLDIVCETAMGRRIY 218

  Fly   193 AMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKR--- 254
            |..|..|..|:|...:...:..|......:::.::.|..:|..:...:.||..|:|.:|.:|
  Fly   219 AQSNSESEYVKAVYGIGSIVQSRQAKIWLQSDFIFSLTAEYKLHQSYINTLHGFSNMVIRERKAE 283

  Fly   255 --IEAHKSGAVSTNAGDEF----TRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTT 313
              |....:...:.||.|.:    .:|::||||.|:.::.:|..|:::::.|||.||||||||||:
  Fly   284 LAILQENNNNNNNNAPDAYDDVGKKKRLAFLDLLIDASKEGTVLSNEDIREEVDTFMFEGHDTTS 348

  Fly   314 SGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFI 378
            :.:|:.::||..|.:.|.::.:|...:.|:.: ...||.:.:..|:||:..||::.|::||||.:
  Fly   349 AAISWTLFLLGCHPEYQERVVEELDSIFGDDK-ETPATMKNLMDMRYLECCIKDSLRLFPSVPMM 412

  Fly   379 GRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG---PFEYVPFSAG 440
            .|...:|..|.|.:||.||...:....|..|.:||..|.:|.|:.|..|...   ||.|:|||||
  Fly   413 ARMVGEDVNIGGKIVPAGTQAIIMTYALHRNPRVFPKPEQFNPDNFLPENCAGRHPFAYIPFSAG 477

  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEV--------LPALDELV--SKDG 479
            ||||||||||:||.|.|:|.::|.:::        |..|.||:  .|||
  Fly   478 PRNCIGQKFAILEEKAVISTVLRKYKIEAVDRREDLTLLGELILRPKDG 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	162/434 (37%)
Cyp4c3	NP_524598.1	CYP4V-like	96..529	CDD:410753	163/435 (37%)