Protein Alignment Cyp4e2 and Cyp313a2

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 132/515 - (25%)
• Similarity: 236/515 - (45%)
• Gaps: 79/515 - (15%)

  Fly     4 VLYIFLALPLLL-VAYLELSTFRRRR---VLNKFNGPRGLPLMGNAHQ-----MGKNPSEILDTV 59
            |:.:.:|..|:| :.:|    :.||:   ::.:..|..||||:||:.:     .|:..|..
  Fly     3 VIQLLIAASLILWIRFL----WSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRT---- 59

  Fly    60 FSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPW---LGLGLLTSTG 121
             ::..::| ..::.||||...|:....|..|.:|:|...|.:|.  |.|:..   :|.||||..|
  Fly    60 -TYMDKHG-STYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSS--QTTNALALSMGYGLLTLQG 120

  Fly   122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFD-FQEQAHYLTLDVICD- 184
            |||...||.:.|||..::|..|..:.|..:...:          ::|| |..|..   .||:.|
  Fly   121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLV----------SVFDSFVGQGE---KDVLSDL 172

  Fly   185 ----------TAMGVSINAMEN-RSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSR 238
                      |.:|..:...:| .:.:|::.::.|.....:..|.|..:|:::.:|........|
  Fly   173 IRWSFAIATQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRR 237

  Fly   239 TLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTID---GRPLNSKELYEE 300
            ....:....|.|:.|::.::......:.            |.|::...|:   ...::..||..|
  Fly   238 DASAINKMINNILDKKLNSNPENYCESE------------LKTVIHRAIELFRNDEMSLMELGAE 290

  Fly   301 VSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFI 365
            .|:.:....:|:...|.:|:.||:...:.|..:|.|.:|....:: |.:.|..::.|:.|||..:
  Fly   291 CSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAK-GIEVTHTDLQQLVYLDRVL 354

  Fly   366 KEAQRVYPSVPFIGRFTEKDY-VIDGDLVPKGTTLNLGLVMLGYNEKVF-KDPHKFRPERFELEK 428
            .|..|:.|||||..|.|.:|. :.:|.::|||.|:::.:.....|...: .:..:|.||.|..||
  Fly   355 NETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEK 419

  Fly   429 ---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN--------FEVLPALDELVSK 477
               ..|:.::|||.|.|||||.::.|:..|..:.||:||        :|.|..:|.:|.|
  Fly   420 IHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	115/442 (26%)
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	116/443 (26%)