Protein Alignment Cyp4e2 and cyp46a1.4

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_005160404.1
• Gene: cyp46a1.4 / 393451
• ZFINID: ZDB-GENE-040426-1224
• Length: 501
• Species: Danio rerio
• Alignment Length: 491
• Identity: 132/491 - (26%)
• Similarity: 234/491 - (47%)
• Gaps: 51/491 - (10%)

  Fly     2 WFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLP----LMGNAHQMGK----NPSEILDT 58
            |.:..||..|..:..|:|....: ...|..|::...|.|    |.|::..:.|    :.|.|.|.
Zfish     5 WILYIIFYLLSAVFTAFLAYCLY-IHYVHQKYDHIPGPPRDNFLFGHSPSLTKSMYADDSLIHDL 68

  Fly    59 VFSWWHQYGKDNFVFWIGT--YSNVLVTSSKYLEFILSSQTLITKSDIYQ-----LTHPWLGLGL 116
            ...|..:||.   |:.|.:  |..::|...:..:.||.|........:|:     ....:||.||
Zfish    69 FLQWAEKYGP---VYRINSLHYIAIVVHCPEATKTILMSPKYTKDPFVYRRLFNLFGKRFLGYGL 130

  Fly   117 LTSTGSK-WHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLD 180
            :|:.... |::.|:::.|||..:.|:......:|.|.:.:..|:.:|.........:..:.:|||
Zfish   131 ITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTLD 195

  Fly   181 VICDTAMGVSINAMENRSSSIVQAFKDMCYN---INMRAFHPLKRNELLYRLAPDYPAYSRTLKT 242
            |||..|.||.:|.:..:.|....|. ::|.|   :::|        :..:||   :|...:.:..
Zfish   196 VICKVAFGVDLNFLAQKDSPFQNAV-ELCLNGMTVDLR--------DPFFRL---FPKNWKLIHQ 248

  Fly   243 LQDFTNEIIAKRIE---AHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVS-- 302
            ::| ..|::.|..|   .::..||..  |::..:.   .|..:|.|..:....|:.:|.:.:.
Zfish   249 IRD-AAELLRKTGEKWIQNRKTAVKN--GEDVPKD---ILTQILKSAEEENVNNTDDLEQMLDNF 307

  Fly   303 -TFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIK 366
             ||...|.:||.:.:|||:..|.|:.:..::...|..||:|..   |:.:.:::.:..||...:|
Zfish   308 VTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEVDEVLGTK---REISNEDLGKFTYLSQVLK 369

  Fly   367 EAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPGP 431
            |..|:||:.|...|:..:|.||:|..:|.|.::.....:....||.||||.||.||||::..|.|
Zfish   370 ETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVMFSSYVSQRLEKFFKDPLKFDPERFDVNAPKP 434

  Fly   432 FE-YVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFE 466
            :. |.||:.|||.|:||.|:.:|.|.|::|:::.||
Zfish   435 YYCYFPFALGPRTCLGQVFSQMEAKVVLAKLLQRFE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	124/458 (27%)
cyp46a1.4	XP_005160404.1	p450	39..495	CDD:278495	124/456 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810