Protein Alignment Cyp4e2 and Cyp4d8

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_523961.2
• Gene: Cyp4d8 / 38841
• FlyBaseID: FBgn0015033
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 189/537 - (35%)
• Similarity: 301/537 - (56%)
• Gaps: 51/537 - (9%)

  Fly     5 LYIFLALPLLLVA--YLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGK-NPSEILDTVFSWWHQY 66
            :.:||.:.||..|  .:.|....|||.:....||...||:|....|.: ||...:.....:..::
  Fly     1 MLLFLLVVLLFGAGWIIHLGQADRRRKVANLPGPICPPLIGAMQLMLRLNPKTFIKVGREYVLKF 65

  Fly    67 GKDNFVFWIGTYSNVLVTS--SKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRK 129
            |....| ||  ::.:|:.|  ::..|.:||||..:.|..:|::...|||.|||.|.|..||:.||
  Fly    66 GHLQRV-WI--FNRLLIMSGDAELNEQLLSSQEHLVKHPVYKVLGQWLGNGLLLSDGKVWHQRRK 127

  Fly   130 MITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAM 194
            :|||.|||:||:.|.||.::.|...::.|...|.| |.||.........||:|.:||||..|.|.
  Fly   128 IITPTFHFSILEQFVEVFDQQSNICVQRLAQKANG-NTFDVYRSICAAALDIIAETAMGTKIYAQ 191

  Fly   195 ENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRT--LKTLQDFTNEIIAKR--- 254
            .|.|:...:|..:....::.|......:.|||:.|...:..:.:|  ::|:|:||.::|.||
  Fly   192 ANESTPYAEAVNECTALLSWRFMSVYLQVELLFTLTHPHLKWRQTQLIRTMQEFTIKVIEKRRQA 256

  Fly   255 IEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFA 319
            :|..:|..:.|...|..::::||.||.||.||:|||||.:.|:.|||.||||||||||||.:||.
  Fly   257 LEDQQSKLMDTADEDVGSKRRMALLDVLLMSTVDGRPLTNDEIREEVDTFMFEGHDTTTSALSFC 321

  Fly   320 VYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEK 384
            ::.||||.:.|.|:.:|..:|:| ::..|..:.:::.::||::..|||:.|:||.||.:||..:.
  Fly   322 LHELSRHPEVQAKMLEEIVQVLG-TDRSRPVSIRDLGELKYMECVIKESLRMYPPVPIVGRKLQT 385

  Fly   385 DY----VIDGD-LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFEL-EKPGPFEYVPFSAGPRN 443
            |:    .:.|| ::|.|:.:.:|:..:....:.|.:|.:|.|||.|. .:..||:.:||||||||
  Fly   386 DFKYTHSVHGDGVIPAGSEIIIGIFGVHRQPETFPNPDEFIPERHENGSRVAPFKMIPFSAGPRN 450

  Fly   444 CIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSA 508
            |||||||.||:|.:::||:|.:|:||               :|             .:.:.|::.
  Fly   451 CIGQKFAQLEMKMMLAKIVREYELLP---------------MG-------------QRVECIVNI 487

  Fly   509 VLTLKSENGLYIRLKER 525
            |  |:||.|..:.:::|
  Fly   488 V--LRSETGFQLGMRKR 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	170/447 (38%)
Cyp4d8	NP_523961.2	CYP4	66..497	CDD:410721	171/465 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449032
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900