Protein Alignment Cyp4e2 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 125/556 - (22%)
• Similarity: 228/556 - (41%)
• Gaps: 116/556 - (20%)

  Fly    13 LLLVAY--LELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNP--SEILDTVFSWWHQYGKDNFV- 72
            |.|||:  |:..|:.:||.:.  :.|..:|| ||..::.:..  :.||...:..:.:.....|.
  Fly    12 LTLVAWWVLQNYTYWKRRGIP--HDPPNIPL-GNTGELWRTMPLAGILKRTYLKFRKQTDGPFAG 73

  Fly    73 FWIGTYSNVLVTSSKYLEFILSSQTLITKSD------IYQ------LTHPWLGLGLLTSTGSKWH 125
            |::.....:::|...:::.:     ||...|      :|.      ||:     .|.|..|.||.
  Fly    74 FYLYAMKYIVITDVDFVKTV-----LIRDFDKFHDRGVYHNEKDDPLTN-----NLATIEGQKWK 128

  Fly   126 KHRKMITPAFH-----------FNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTL 179
            ..|:.:|..|.           .|:..:...|::|   |.....:|:...|.:..|       |.
  Fly   129 NLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDE---KISSSSQTLEVTDIVSRF-------TS 183

  Fly   180 DVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLY---RLAPDYPAYSRTLK 241
            |||...|.|:..|::.:..:..||    |.|:......|....:.|::   :||... .:...|.
  Fly   184 DVIGICAFGLKCNSLRDPKAEFVQ----MGYSALRERRHGWLVDLLIFGMPKLAVKL-GFQFLLP 243

  Fly   242 TLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLL--------SSTIDGRPLNSKELY 298
            ::|.|..:|:...|:......|:.|          .|:|||:        ....:|...|  |:.
  Fly   244 SVQKFYMKIVQDTIDYRMKRKVTRN----------DFMDTLIDMKQQYDKGDKENGLAFN--EVA 296

  Fly   299 EEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMG--NSELGRDATFQEISQMKYL 361
            .:...|...|.:..::.:.|.:|.|:.:||.|.||..|...|:.  |.:|..|:    :..:.|:
  Fly   297 AQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDS----MQDLFYM 357

  Fly   362 DLFIKEAQRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF 424
            :..|.|:.|.:|.|..:.|...|.|.....  .:..||.:.:..:.:.::.:.:.:|.||.||||
  Fly   358 EKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERF 422

  Fly   425 ---ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIG 486
               :::|.....::||.||||||||.:|..:::...::.:|.||..
  Fly   423 DEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRF------------------- 468

  Fly   487 LPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRL 522
                |...:.|...||  .::.:| |.||.|:::.:
  Fly   469 ----ELHPKTPVPMKY--TINNLL-LGSEGGIHLNI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	108/477 (23%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	117/532 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810