Protein Alignment Cyp4e2 and Cyp6a13

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 125/531 - (23%)
• Similarity: 229/531 - (43%)
• Gaps: 92/531 - (17%)

  Fly     1 MWFVLYIFLALPLLLVAYLEL----STFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFS 61
            |..:|.:...:.|||  |::|    |.:.||.|.    |.|.:...||...:|::        ..
  Fly     1 MLTLLVLVFTVGLLL--YVKLRWHYSYWSRRGVA----GERPVYFRGNMSGLGRD--------LH 51

  Fly    62 W----WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQ---LTH-----PWLGL 114
            |    ...|.|...|.....|...:..|...::..|....:|.....:.   |.|     |..|
  Fly    52 WTDINLRIYRKFRGVERYCGYFTFMTKSLFIMDLELIRDIMIRDFSSFADRGLFHNVRDDPLTG- 115

  Fly   115 GLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTL 179
            .||...|.:|...|:.:|..|....::.....|.|...|..:..: :..|:  .:.::.....|.
  Fly   116 NLLFLDGPEWRWLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACR-LQVGE--IEAKDLCARFTT 177

  Fly   180 DVICDTAMGVSINAMENRSS-------SIVQAFKDMCYNINMRAF---HPLKRNELLYRL-APDY 233
            |||...|.|:..|::::..|       |:.|   :..:::.::||   .|....:|.:|| .|:.
  Fly   178 DVIGSCAFGLECNSLQDPESQFRRMGRSVTQ---EPLHSVLVQAFMFAQPELARKLRFRLFRPEV 239

  Fly   234 PA-YSRTLKTLQDFTNEIIAKRIEAHKSGAVS--TNAGDEFTRKKMAFLDTLLSSTIDGRPLNSK 295
            .. :..|::...|:     .:|...|::..:.  ...|:|..:..::|                :
  Fly   240 SEFFLDTVRQTLDY-----RRRENIHRNDLIQLLMELGEEGVKDALSF----------------E 283

  Fly   296 ELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVM--GNSELGRDATFQEISQM 358
            ::..:...|...|.||:::.:||.:|.|:.:.|.|.:|..|...|:  .|.:|    |:..:.:|
  Fly   284 QIAAQALVFFLAGFDTSSTTMSFCLYELALNPDVQERLRVEVLAVLKRNNQKL----TYDSVQEM 344

  Fly   359 KYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD--LVPKGTTLNLGLVMLGYNEKVFKDPHKFRP 421
            .|||..:.|..|.||.:|.:.|.:.|:|.|...  ::..|:.:.:.:..:.::.:::.||.||.|
  Fly   345 PYLDQVVAETLRKYPILPHLLRRSTKEYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDP 409

  Fly   422 ERFELEK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEV-------LPALDELVS 476
            .|||.|:   ..||.|:||..|||||||::|..|::|..:..::|:|:.       :|.  :..|
  Fly   410 SRFEPEEIKARHPFAYLPFGEGPRNCIGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPL--KFSS 472

  Fly   477 KDGYISTTIGL 487
            ::..|||..|:
  Fly   473 RNFLISTQEGV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	107/456 (23%)
Cyp6a13	NP_610390.1	CYP6-like	67..484	CDD:410679	105/451 (23%)