Protein Alignment Cyp4e2 and Cyp6a2

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 144/570 - (25%)
• Similarity: 245/570 - (42%)
• Gaps: 113/570 - (19%)

  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGL------PLMGNAHQMGKNPSEIL-DT 58
            |:.::|:.:|:..|| |||      ..|..|.:| .||:      ||.||  .:|...:.:: |.
  Fly     1 MFVLIYLLIAISSLL-AYL------YHRNFNYWN-RRGVPHDAPHPLYGN--MVGFRKNRVMHDF 55

  Fly    59 VFSWWHQYGKDNFVFWIGTY---------------SNVLVTSSKYLEFILSSQTLITKSDIYQLT 108
            .:.::::|.|..|.| :|.|               .|:|:  ..:..|....|....:.|  .||
  Fly    56 FYDYYNKYRKSGFPF-VGFYFLHKPAAFIVDTQLAKNILI--KDFSNFADRGQFHNGRDD--PLT 115

  Fly   109 HPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHL-KTVAAGDN--IFDF 170
            .     .|....|.||...|:.:||.|....::.....:.:.|.:|:|.: :.|.|..|  :.:.
  Fly   116 Q-----HLFNLDGKKWKDMRQRLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEI 175

  Fly   171 QEQAHYLTLDVICDTAMGVSINAMENRSSSI----VQAFKDMCYN--INMRAF-HPLKRNELLYR 228
            :|.....|.|||...|.|:..|.:....|..    .:.|.||.:.  :.|..| .|...:.|..|
  Fly   176 KELMARFTTDVIGTCAFGIECNTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMR 240

  Fly   229 LAPD--YPAYSR------TLKTLQDF-TNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLS 284
            :.|:  :..:.|      .|:..::| .|:.:...||..:.|.|:.:.|:
  Fly   241 MMPEDVHQFFMRLVNDTIALRERENFKRNDFMNLLIELKQKGRVTLDNGE--------------- 290

  Fly   285 STIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRD 349
             .|:|..:.  ||..:|..|...|.:|::|.:|:.:|.|:::||.|.:|..|.:.|:...|  ..
  Fly   291 -VIEGMDIG--ELAAQVFVFYVAGFETSSSTMSYCLYELAQNQDIQDRLRNEIQTVLEEQE--GQ 350

  Fly   350 ATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD---LVPKGTTLNLGLVMLGYNEK 411
            .|::.|..|.||:..|.|..|:|..||.:.|....|||:.|.   ::.|||.:.:.......:|.
  Fly   351 LTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPGHEKLVIEKGTQVIIPACAYHRDED 415

  Fly   412 VFKDPHKFRPERFELEKPG---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDE 473
            ::.:|..|.||||..||..   ..|::||..|||||||.:|..::.:..:::||..|.|
  Fly   416 LYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRFGQMQARIGLAQIISRFRV------ 474

  Fly   474 LVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523
                  .:..|..:|           .||.|:   .:.|.:..|:|:|::
  Fly   475 ------SVCDTTEIP-----------LKYSPM---SIVLGTVGGIYLRVE 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	124/480 (26%)
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	130/523 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810