Protein Alignment Cyp4e2 and Cyp4d21

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_609129.2
• Gene: Cyp4d21 / 34036
• FlyBaseID: FBgn0031925
• Length: 511
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 181/527 - (34%)
• Similarity: 278/527 - (52%)
• Gaps: 49/527 - (9%)

  Fly     1 MWFVLYIFLALPLLLVAYL--------ELSTFRRRRVLNKFNGPRGLPLMGNAHQ-MGKNPSEIL 56
            ||    |.|.:.:|::..:        .::||.:.|:|    ||..:|::||..| :...|...:
  Fly     1 MW----ILLGIAVLIMTLVWDNSRKQWRVNTFEKSRIL----GPFTIPIVGNGLQALTLRPENFI 57

  Fly    57 DTVFSWWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTG 121
            .....::::||| .|..||.....:.....||.|.||||.||:.|:.:|:....:||.|||.|||
  Fly    58 QRFGDYFNKYGK-TFRLWILGECLIYTKDLKYFESILSSSTLLKKAHLYRFLRDFLGDGLLLSTG 121

  Fly   122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTA 186
            :||...||::.|||||..|::|.|:|:.||...::.||..|.|....|..:......|||..:||
  Fly   122 NKWTSRRKVLAPAFHFKCLENFVEIMDRNSGIMVEKLKNYADGKTCVDLFKFVSLEALDVTTETA 186

  Fly   187 MGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPD--YPAYSRTLKTLQDFTNE 249
            |||.:||....:....:|.|.:.|..:.|......|...|:.||..  |....:.:..:||||::
  Fly   187 MGVQVNAQNEPNFPYTKALKSVVYIESKRLASVSMRYNWLFPLAAPLVYRRLQKDIAIMQDFTDK 251

  Fly   250 IIAKRIEAHKSGAVSTNAGDEFTRK-------------KMAFLDTLLSSTIDGRPLNSKELYEEV 301
            :|.:|      .|:...|..:.|.|             ||..||.||.:|||.:||:..::.|||
  Fly   252 VIRER------RAILERARADGTYKPLIMGDDDIGGKAKMTLLDILLQATIDNKPLSDVDIREEV 310

  Fly   302 STFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIK 366
            ..|:|.|.||||||||.|::.:|||...|..:::|...|:| .:.....|..::.::||||..||
  Fly   311 DVFIFAGDDTTTSGVSHALHAISRHPKVQECIYEELVSVLG-PDPDASVTQTKLLELKYLDCVIK 374

  Fly   367 EAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF----ELE 427
            |..|::|.||.:||:..:|..|....:|..|::.|....:..:.:.|.||..|:|||:    ...
  Fly   375 ETMRLHPPVPILGRYIPEDLKIGEITIPGNTSILLMPYYVYRDPEYFPDPLVFKPERWMDMKTTS 439

  Fly   428 KPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYI--STT---IGL 487
            ...|..|:|||:||:||||||||.|::|.::||:||::|:||...:|.:...:|  |:|   :||
  Fly   440 NTPPLAYIPFSSGPKNCIGQKFANLQMKALISKVIRHYELLPLGADLKATYTFILSSSTGNNVGL 504

  Fly   488 PDAERKK 494
            ....|.|
  Fly   505 KPRTRVK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	162/453 (36%)
Cyp4d21	NP_609129.2	p450	35..482	CDD:278495	163/454 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449033
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900