Protein Alignment Cyp4e2 and Cyp3a44

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 506
• Identity: 121/506 - (23%)
• Similarity: 241/506 - (47%)
• Gaps: 65/506 - (12%)

  Fly     7 IFLALPLLLVAYLELST---FRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWW----- 63
            :.||:.|:|:......|   |:::.:    .||:.||.:|.          :|:.....|
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGI----PGPKPLPFLGT----------VLNYYTGIWKFDME 63

  Fly    64 --HQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLT-----STG 121
              .:||| .:..:.|....:::|..:.::.:|....|    .::.....:..:|:::     |..
Mouse    64 CYEKYGK-TWGLFDGQTPLLVITDPETIKNVLVKDCL----SVFTNRREFGPVGIMSKAISISKD 123

  Fly   122 SKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTA 186
            .:|.::|.:::|.|....|::...|:.:.....:|:|:..|........::.....::|||..|:
Mouse   124 EEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMPVAMKDVLGAYSMDVITSTS 188

  Fly   187 MGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTN--- 248
            .||:::::.|.....|:..|..   :.:..|.||..:.:|:.|..  |.|.  :..:..|.|
Mouse   189 FGVNVDSLNNPEDPFVEEAKKF---LRVDFFDPLLFSVVLFPLLT--PVYE--MLNICMFPNDSI 246

  Fly   249 EIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVS------TFMFE 307
            |...|.::..:...:.:|     .:.::.||..:::|..:.:..:|.:.:..:.      .|:..
Mouse   247 EFFKKFVDRMQESRLDSN-----QKHRVDFLQLMMNSHNNSKDKDSHKAFSNMEITVQSIIFISA 306

  Fly   308 GHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVY 372
            |::||:|.:||.:|.|:.|.|.|:||..|..:.:.|.   ...|...:.:|:|||:.:.|..|:|
Mouse   307 GYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPNK---ATPTCDTVMEMEYLDMVLNETLRLY 368

  Fly   373 PSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG---PFEY 434
            |.|..:.|..:||..::|..:|||:.:.:....|.::.:.:.||.:|:||||..|..|   |:.|
Mouse   369 PIVTRLERVCKKDVELNGVYIPKGSMVMIPSYALHHDPQHWPDPEEFQPERFSKENKGSIDPYVY 433

  Fly   435 VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV----SKDGYI 481
            :||..|||||||.:|||:.:|..|:|:::||...|..:..:    |:.|.:
Mouse   434 LPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIPLKLSRQGIL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	112/457 (25%)
Cyp3a44	NP_796354.1	p450	39..494	CDD:278495	115/476 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810