Protein Alignment Cyp4e2 and Cyp311a1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 145/525 - (27%)
• Similarity: 250/525 - (47%)
• Gaps: 54/525 - (10%)

  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQ 65
            :|.:|.|.|.:.:|:..:..|      |:.:...||...||:|||..:||...|.:..||:....
  Fly     3 LWPLLLITLTIWILVRKWTLL------RLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVFTELRD 61

  Fly    66 YGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKM 130
            .....:...:|....|.:.|::.....|...|| .|:|.:....|.:|.|||.|.|:.|.:.|::
  Fly    62 RFGATYRLRLGPQLWVFLHSAEETRQALHDPTL-RKADTFMQLEPLIGNGLLISHGAHWTRQRRL 125

  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAME 195
            :||||...:|:.|...:..:..:.:..|.  |......:..|......||.|.||:||..::...
  Fly   126 LTPAFQPQLLRSFAPAIGGHVERLVGRLG--ATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQS 188

  Fly   196 NRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI-EAHK 259
            ...|.|:|||......:..|..:||..::.:::....:......|:.:......:|.||. |...
  Fly   189 VDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELLD 253

  Fly   260 SGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLS 324
            .|..:..|.:        .|||||.:..:|:.|:.:|:.:|::||:|.|.||||:.:||.:|.|:
  Fly   254 MGEPAGRAHN--------LLDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALA 310

  Fly   325 RHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVID 389
            :..:.|.:|.||.::|..:.....||    ::.:.||:..|||..|:|..||..||.|.:...|.
  Fly   311 KFPETQTRLRKELQDVALDETTDLDA----LNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIG 371

  Fly   390 GDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELE----KPGPFEYVPFSAGPRNCIGQKFA 450
            |.....|.||.:.:..|.::::.:.||:.|:|||:..|    .|..|.|:|||.||..|||::::
  Fly   372 GRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYS 436

  Fly   451 LLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSE 515
            ||.:|.:.::::|.|::     ||                 ..::.|.|      |.|.:.||::
  Fly   437 LLLMKLLTARLVREFQM-----EL-----------------SPEQAPLR------LEAQMVLKAQ 473

  Fly   516 NGLYI 520
            .|:.:
  Fly   474 QGINV 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	126/456 (28%)
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	126/456 (28%)