Protein Alignment Cyp4e2 and Cyp4ae1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 195/538 - (36%)
• Similarity: 295/538 - (54%)
• Gaps: 64/538 - (11%)

  Fly     7 IFLALPLLLVAYLELSTFRRRRVLNKFNGP-RG-------LPLMGNAHQMGK-NPSEILDTVFSW 62
            :.:.|..|||..|..|.|  |..|.:...| :|       :||:|.|.||.. .|..:.|....:
  Fly     2 LVVLLVALLVTRLVASLF--RLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEY 64

  Fly    63 WHQYGKDNFVFWIGTYSN--VLVTSS-KYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKW 124
            ..::|:.    ::||...  |:||:. ::::.:|..|..:.|..:|.....|||.|||.|.|.:|
  Fly    65 VKRFGRS----FMGTVLGHVVMVTAEPRHIDALLQGQHQLKKGTMYFALRGWLGDGLLLSRGKEW 125

  Fly   125 HKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGV 189
            |..||:|||.|||:||:.|.||.:..|:..::.|:|::.|:.:.:.........||:|.:|||||
  Fly   126 HTMRKIITPTFHFSILEQFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIITETAMGV 190

  Fly   190 SINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKT----LQDFTNEI 250
            :::| :...|.:|.|.||:...:..|...|......|:||.  :|:..|..:.    |.:|||.|
  Fly   191 NVDA-QGADSEVVHAVKDLTNILATRFMRPHLLFPHLFRLC--WPSGFRKQQAGVICLHEFTNGI 252

  Fly   251 IAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSG 315
            |.:|     ...::..|..:...|..|.|||||.:|:||:||..|::.:||:||:|||||||||.
  Fly   253 IEQR-----RRLLAREANQDKPTKPHALLDTLLRATVDGQPLTDKQIRDEVNTFIFEGHDTTTSA 312

  Fly   316 VSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGR 380
            |||.:||||||:..|:|||:|.|...| .:|.|.....:.:.:.||...:||:.|:||.:|.:.|
  Fly   313 VSFCLYLLSRHEAVQQKLFEELRMHYG-QDLFRGVILSDFATLPYLSCVVKESLRLYPPIPAVAR 376

  Fly   381 FTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKPGPFEYVPFSAGPR 442
            ..|||.|||...:|.||.:.:.|..|..:|.:|.||..|:|||.   |..:..|:.|:|||||||
  Fly   377 CLEKDLVIDEGYIPVGTNVVVLLWQLLRDEAIFTDPLVFQPERHLGEEAPRLSPYSYIPFSAGPR 441

  Fly   443 NCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILS 507
            |||||||||||:||:|:|:||::::||               :| .|.|.              |
  Fly   442 NCIGQKFALLEMKTMVTKVIRHYQLLP---------------MG-ADVEP--------------S 476

  Fly   508 AVLTLKSENGLYIRLKER 525
            ..:.|:|::|:.:.|:.|
  Fly   477 IKIVLRSKSGVNVGLRPR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	173/461 (38%)
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	171/451 (38%)