Protein Alignment Cyp4e2 and cyp26a1

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_571221.2
• Gene: cyp26a1 / 30381
• ZFINID: ZDB-GENE-990415-44
• Length: 492
• Species: Danio rerio
• Alignment Length: 495
• Identity: 113/495 - (22%)
• Similarity: 192/495 - (38%)
• Gaps: 89/495 - (17%)

  Fly     9 LALPLLL----VAYLELSTFRR-----RRVLNKFNGPRGLPLMG--------------------- 43
            :.||:||    |...|:...||     |..|..  |..|||.:|
Zfish    14 IVLPVLLFLAAVKLWEMLMIRRVDPNCRSPLPP--GTMGLPFIGETLQLILQRRKFLRMKRQKYG 76

  Fly    44 ---NAHQMGKNPSEILDTVFSWWHQYGKDNF-VFWIGTYSNVLVTSSKYLEFILSSQTLITKSDI 104
               ..|..| ||     ||    ...|.||. ...:|.:..|.|.....:..||.|.||   |::
Zfish    77 CIYKTHLFG-NP-----TV----RVMGADNVRQILLGEHKLVSVQWPASVRTILGSDTL---SNV 128

  Fly   105 YQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFD 169
            :.:.|               ...:|.|..||..:.|:.:..|:.:.....|:..   ...|:...
Zfish   129 HGVQH---------------KNKKKAIMRAFSRDALEHYIPVIQQEVKSAIQEW---LQKDSCVL 175

  Fly   170 FQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYP 234
            ...:...|...:.....:|.....::.....:|:||::|..|              |:.|..|.|
Zfish   176 VYPEMKKLMFRIAMRILLGFEPEQIKTDEQELVEAFEEMIKN--------------LFSLPIDVP 226

  Fly   235 AYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYE 299
             :|...:.|:  ....|..:||.:....:..:..:...:.|.|....:.:|.....|.:.:.:.|
Zfish   227 -FSGLYRGLR--ARNFIHSKIEENIRKKIQDDDNENEQKYKDALQLLIENSRRSDEPFSLQAMKE 288

  Fly   300 EVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQRE--VMGNSELGRDATFQEISQMKYLD 362
            ..:..:|.||:||.|..:..|..|..:.:..:|:.:|.:|  .||....|:..:.:.:.|:||..
Zfish   289 AATELLFGGHETTASTATSLVMFLGLNTEVVQKVREEVQEKVEMGMYTPGKGLSMELLDQLKYTG 353

  Fly   363 LFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF--- 424
            ..|||..|:.|.||...|...|.:.::|..:|||..:...:........||.:..:|:||||
Zfish   354 CVIKETLRINPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADVFPNKDEFQPERFMSK 418

  Fly   425 ELEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRN 464
            .||....|.|:||..|.|.|:|::||.:.:|..:.::.::
Zfish   419 GLEDGSRFNYIPFGGGSRMCVGKEFAKVLLKIFLVELTQH 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	103/460 (22%)
cyp26a1	NP_571221.2	p450	14..487	CDD:299894	113/495 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910