Protein Alignment Cyp4e2 and Cyp4f39

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_234837.3
• Gene: Cyp4f39 / 299566
• RGDID: 1308796
• Length: 550
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 172/548 - (31%)
• Similarity: 275/548 - (50%)
• Gaps: 84/548 - (15%)

  Fly     7 IFLALPLLLVAYLELSTFR---RRRVLNKFNGPRGLP-LMGN-----AHQMG-KNPSEILDTVFS 61
            :||...|||.|:...|.||   ||  |:.|..|.|.. |:|:     .::.| :|..::|||:
  Rat    32 LFLLFRLLLQAFKLFSDFRITCRR--LSCFPEPPGRHWLLGHMSMYLPNEKGLQNEKKVLDTM-- 92

  Fly    62 WWHQYGKDNFVFWIGTYSNVLV-TSSKYLEFILSSQTLITKSD--IYQLTHPWLGLGLLTSTGSK 123
              |..    .:.|:|.:..:|| ....|::.:|.:...|...|  .|....||||.|||.|.|:|
  Rat    93 --HHI----ILAWVGPFLPLLVLVHPDYIKPVLGASAAIAPKDEFFYSFLKPWLGDGLLISKGNK 151

  Fly   124 WHKHRKMITPAFHFNILQDFHEVMNEN----STKFIKHLKTVAAGD-NIFDFQEQAHYLTLDVIC 183
            |.:||:::||||||:||:.:.::.|::    ..|:.:||   |.|. ..||..|....:|||.:.
  Rat   152 WSRHRRLLTPAFHFDILKPYMKIFNQSVNIMHAKWRRHL---AEGSVTSFDMFEHVSLMTLDSLQ 213

  Fly   184 DTAMGVSINAMENRS---SSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQD 245
            ......|.:..|..|   |||:: ...:......|..|.|   :.:|.|..|...:.:...|:.:
  Rat   214 KCVFSYSSDCQEKLSDYISSIIE-LSALVVRRQYRLHHYL---DFIYYLTADGRRFRQACDTVHN 274

  Fly   246 FTNEIIAKRIEA-HKSGA---VSTNAGDEFTRKKMAFLDT-LLSSTIDGRPLNSKELYEEVSTFM 305
            ||.|:|.:|..| .:.||   :....|     |.:.|:|. ||:...:|:.|:.:::..|..|||
  Rat   275 FTTEVIQQRRRALRELGAEAWLKAKQG-----KTLDFIDVLLLAKDEEGKELSDEDIRAEADTFM 334

  Fly   306 FEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQR 370
            |||||||:||:|:|::.|:::.:.|.|..:|.:|||...|| .:..:.:::|:.:..:.|||:.|
  Rat   335 FEGHDTTSSGLSWALFNLAKYPEYQDKCREEIQEVMKGREL-EELDWDDLTQLPFTTMCIKESLR 398

  Fly   371 VYPSVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP---GP 431
            .:|.|..|.|...:|..: ||.::|||....:.:....||..|:.|...:.|.||:.:.|   .|
  Rat   399 QFPPVTLISRRCTEDIKLPDGRIIPKGIICLVSIYGTHYNPLVWPDSKVYNPYRFDPDIPQQRSP 463

  Fly   432 FEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERK-KR 495
            ..:|||||||||||||.||:.|::.||:..:..|.:                   ..|..|| :|
  Rat   464 LAFVPFSAGPRNCIGQSFAMAEMRVVVALTLLRFRL-------------------SVDRTRKVRR 509

  Fly   496 DPYRHKYDPILSAVLTLKSENGLYIRLK 523
            .|           .|.|::||||::.::
  Rat   510 KP-----------ELILRTENGLWLNVE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	149/472 (32%)
Cyp4f39	XP_234837.3	CYP4F	82..523	CDD:410772	154/491 (31%)