Protein Alignment Cyp4e2 and Cyp4a3

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 163/562 - (29%)
• Similarity: 257/562 - (45%)
• Gaps: 115/562 - (20%)

  Fly     3 FVLYIFLALPLLLVAYLELSTFRRR---RVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWH 64
            |:|.:||.|...:..||     ||:   :.|.||               ...||..|     |.|
  Rat    23 FLLSLFLVLFKAVQFYL-----RRQWLLKALEKF---------------PSTPSHWL-----WGH 62

  Fly    65 QYGKDNF---VFWI------------GTYSNVLVTSSKYLEFILSSQTLITKSD-----IYQLTH 109
            ......|   :.|:            |:.:.||:....|::.:|.      :||     |||...
  Rat    63 DLKDREFQQVLTWVEKFPGACLQWLSGSKTRVLLYDPDYVKVVLG------RSDPKASGIYQFLA 121

  Fly   110 PWL----GLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDN---I 167
            ||:    |.|||...|.||.:|.:|:|||||:.||:.:.::|.::.:..:...:.:...|:   |
  Rat   122 PWIVSGTGYGLLLLNGKKWFQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDDQDHPLEI 186

  Fly   168 FDFQEQAHYLTLDVICDTAMGVSIN-----AMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLY 227
            |      ||::| :..||.|..:.:     .::..|.|..:|.:|:......|.......|.::|
  Rat   187 F------HYVSL-MTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIY 244

  Fly   228 RLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKK--MAFLDTLLSSTI-DG 289
            .::.|.....|..:...:.|:.:|..|     ...:......:..|||  :.|||.||.:.: ||
  Rat   245 NMSSDGRLSRRACQIAHEHTDGVIKMR-----KAQLQNEEELQKARKKRHLDFLDILLFAKMEDG 304

  Fly   290 RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQE 354
            :.|:.::|..||.||||||||||.||:|:..|.|:.|.:.|.:..:|.:.::|:   |...|:..
  Rat   305 KSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD---GTSVTWDH 366

  Fly   355 ISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHK 418
            :.|:.|..:.||||.|:||.||.:.|........ ||..:|||.|..:.:..|.:|...:.:|..
  Rat   367 LDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKV 431

  Fly   419 FRPERFELEKP-GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYIS 482
            |.|.||..:.| ....|:|||.|.|||||::||:.|:|..|:..:..||:||
  Rat   432 FDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP------------- 483

  Fly   483 TTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKE 524
                         ||.|   .|:..|.|.|||:||:::|||:
  Rat   484 -------------DPTR---IPVPMARLVLKSKNGIHLRLKK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	135/470 (29%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	143/486 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750