Protein Alignment Cyp4e2 and Cyp4f5

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_775147.1
• Gene: Cyp4f5 / 286905
• RGDID: 708364
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 474
• Identity: 137/474 - (28%)
• Similarity: 235/474 - (49%)
• Gaps: 57/474 - (12%)

  Fly    68 KDNFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSD--IYQLTHPWLGLGLLTSTGSKWHKHRK 129
            :|..:.|:|....|| :....::..:|.:..|:...|  ..:...||||.||..|:|.||.:||:
  Rat    85 RDIHLCWLGPVIPVLRLVDPAFVAPLLQAPALVAPKDTTFLRFLKPWLGDGLFLSSGDKWSRHRR 149

  Fly   130 MITPAFHFNILQDFHEVMNENSTKFIKHLK---TVAAGDNIFDFQEQAHYLTLDVICDTAMGVSI 191
            ::||||||:||:.:.::.|::..  |.|.|   ....|....:..|....:|||.:.....|...
  Rat   150 LLTPAFHFDILKPYVKIFNQSVN--IMHAKWKHLCLEGSARLEMFENISLMTLDSLQKCLFGFDS 212

  Fly   192 NAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIE 256
            |..|: .|..:.|..::...|..|:.......:.||....|...:.:....:.:||:.:|.:|
  Rat   213 NCQES-PSEYISAILELSSLIIKRSQQLFLYLDFLYYRTADGRRFRKACDLVHNFTDAVIRER-- 274

  Fly   257 AHKSGAVSTNAGDEFTRKK-------MAFLDTLLSSTID-GRPLNSKELYEEVSTFMFEGHDTTT 313
               ...:|:...|||...|       :.|:|.||.:..: |:.|:.:::..|..||||.|||||.
  Rat   275 ---RRLLSSQGTDEFLESKTKSKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTA 336

  Fly   314 SGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVY-PSVPF 377
            |.:|:.:|.|:||.:.|.:..:|..|::.:.| ..:..:.:::|:.:|.:.|||:.|:: |::..
  Rat   337 SALSWILYNLARHPEYQERCRQEVWELLRDRE-PEEIEWDDLAQLPFLTMCIKESLRLHPPAIDL 400

  Fly   378 IGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELE---KPGPFEYVPFSA 439
            :.|.|:...:.||.::|||....:.:..:.:|..|:.||..|.|.||:.|   |..|..::||||
  Rat   401 LRRCTQDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVFDPFRFDSENRQKRSPLSFIPFSA 465

  Fly   440 GPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDP 504
            ||||||||.||:.|:|.||:..:..|.|                   |||.:..:|.|
  Rat   466 GPRNCIGQTFAMNEMKVVVALTLLRFRV-------------------LPDDKEPRRKP------- 504

  Fly   505 ILSAVLTLKSENGLYIRLK 523
                .:.|::|.||::|::
  Rat   505 ----EIILRAEGGLWLRME 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	127/418 (30%)
Cyp4f5	NP_775147.1	p450	52..516	CDD:278495	136/469 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640