Protein Alignment Cyp4e2 and Cyp4f4

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 156/558 - (27%)
• Similarity: 262/558 - (46%)
• Gaps: 84/558 - (15%)

  Fly     2 WFVLYIFLALPLLLV---------------------AYLELSTFRRRRVLNKFNGPRGLPLMGNA 45
            |..|.:..:||.||:                     .|..|..|.:....|.|.|..|  ::...
  Rat     8 WLGLRLETSLPWLLLLLIGASWLLVRVLTQTYIFYRTYQHLCDFPQPPKWNWFLGHLG--MITPT 70

  Fly    46 HQMGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSDI--YQL 107
            .|..|..::::.|.        ...|:.|:|....:: :.....:..:||:...:...::  |..
  Rat    71 EQGLKQVTKLVATY--------PQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSF 127

  Fly   108 THPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK---TVAAGDNIFD 169
            ..||||.|||.|.|.||..||:|:|||||||||:.:.::.|:::.  |.|.|   ..:.|....|
  Rat   128 LKPWLGDGLLLSDGDKWSCHRRMLTPAFHFNILKPYVKIFNDSTN--IMHAKWQDLASGGSARLD 190

  Fly   170 FQEQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYP 234
            ..:....:|||.:.........|..| :.|..:.|..::...:..|....|...:.||:|..:..
  Rat   191 MFKNISLMTLDSLQKCVFSFDSNCQE-KPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGR 254

  Fly   235 AYSRTLKTLQDFTNEIIAKRIEA----HKSGAVSTNAGDEFTRKKMAFLDT-LLSSTIDGRPLNS 294
            .:.:..|.:.:||:.:|..|..|    |:...:...|    ..|.:.|:|. ||:...||:.|:.
  Rat   255 RFHKACKLVHNFTDAVIQGRRRALPSQHEDDILKAKA----RSKTLDFIDVLLLTKDEDGKELSD 315

  Fly   295 KELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMK 359
            :::..|..||||||||||.||:|:.:|.|:||.:.|.:..:|.||::.:.| ..:..:.:::|:.
  Rat   316 EDIRAEADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRE-STEIEWDDLAQLP 379

  Fly   360 YLDLFIKEAQRVYPSVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPER 423
            :|.:.|||:.|::|.|..|.|...:|.|: ||.::|||....:.:....:|..|:.||..:.|.|
  Rat   380 FLTMCIKESLRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFR 444

  Fly   424 FE---LEKPGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTI 485
            |:   ::...|..::||||||||||||.||:.|:|..::..:..|.|
  Rat   445 FDPENIKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRV------------------ 491

  Fly   486 GLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523
             |||.:..:|.|           .|.|::|.||::|::
  Rat   492 -LPDDKEPRRKP-----------ELILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	134/448 (30%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	141/486 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650