Protein Alignment Cyp4e2 and Cyp4f17

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001094915.1
• Gene: Cyp4f17 / 208285
• MGIID: 3646233
• Length: 524
• Species: Mus musculus
• Alignment Length: 492
• Identity: 149/492 - (30%)
• Similarity: 247/492 - (50%)
• Gaps: 56/492 - (11%)

  Fly    48 MGKNPSEILDTVFSWWHQYGKDNFVFWIGTYSNVL-VTSSKYLEFILSSQTLITKSDI--YQLTH 109
            |.||..|.|..:....||: .|..:.|||.:..:| :...|::..||.:...:...::  |....
Mouse    66 MVKNNEEGLQLLTERSHQF-HDVHLCWIGPFYPILRLIHPKFIGPILQASAAVAPKEMIFYGFLK 129

  Fly   110 PWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLK---TVAAGDNIFDFQ 171
            ||||.|||.|.|.||.:||.::||||||:||:.:  :.|.|.:..|.|.|   ....|....|..
Mouse   130 PWLGDGLLVSAGEKWSRHRHLLTPAFHFDILKPY--MKNFNKSVNIMHAKWQRLTTKGTACLDML 192

  Fly   172 EQAHYLTLDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAY 236
            |....:|||.:.:.......|..|: .|..:.|.:::...|..|...|....:.||....|...:
Mouse   193 EHISLMTLDSLQNCVFSFDSNCQES-PSEYIAAIQELSSLIVKRHHQPFLYLDFLYYCTADGRRF 256

  Fly   237 SRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKK-----MAFLDTLLSSTID-GRPLNSK 295
            .:....:.:||:.:|.:|     ...:|:...|||.:.|     :.|:|.||.:..: |:.|:.:
Mouse   257 RKACDLVHNFTDAVIRER-----RRTLSSQNLDEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDE 316

  Fly   296 ELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKY 360
            ::..|..||||.|||||.|.:|:.:|.|:||.:.|.:..:|.:|::...| .::..:.:::|:.:
Mouse   317 DIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGRE-PQEIEWDDLAQLPF 380

  Fly   361 LDLFIKEAQRVYPSVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF 424
            |.:.|||:.|::|.|..|.|...:|.|: ||.::||||...:.:..:.:|.:|:.||..:.|.||
Mouse   381 LTMCIKESLRLHPPVTVISRCCTQDVVLPDGRVIPKGTDCVISIFGVHHNPEVWPDPEVYDPFRF 445

  Fly   425 ELEKP---GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIG 486
            :.|.|   .|..::||||||||||||.||:.|:|..::..:..|.|||.
Mouse   446 DPENPQKRSPLAFIPFSAGPRNCIGQTFAMREMKVALALTLLRFRVLPG---------------- 494

  Fly   487 LPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523
              |.|.:::..            |.|::|.||::|::
Mouse   495 --DKEPRRKPE------------LILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	139/436 (32%)
Cyp4f17	NP_001094915.1	p450	52..515	CDD:365848	148/488 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845190
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650