Protein Alignment Cyp4e2 and cyp-37B1

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_507109.1
• Gene: cyp-37B1 / 180093
• WormBaseID: WBGene00009226
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 181/509 - (35%)
• Similarity: 282/509 - (55%)
• Gaps: 42/509 - (8%)

  Fly     3 FVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMG-----NAHQMGKNPSEILDTVFSW 62
            |::.|||....|:..::. ...|..:.:.||:||...|::|     |...:.|..::.:: :..:
 Worm    10 FLITIFLFYYKLIYNFIR-DRLRIYKYMRKFDGPYSFPIIGTLYMVNIFDISKFTTQSME-LAQY 72

  Fly    63 WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKH 127
            :.|.|......|:|....:.|.:.::.:.||.|..:|||::.|.:..||||.||||||||||.:.
 Worm    73 YCQKGCGTIGLWLGPVPLIAVINPQHAKEILESNEVITKAEEYDILFPWLGTGLLTSTGSKWRQR 137

  Fly   128 RKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSIN 192
            |||:||||||.:|.||..|.:..:..|::.:|..|......|.......|.|||||||:|||:|:
 Worm   138 RKMLTPAFHFKVLNDFLSVHDYQAKVFLEQIKPYADSGKEVDLFPYIKRLALDVICDTSMGVTID 202

  Fly   193 AMENRSSSIVQAFK---DMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKR 254
            |..|.....|::.:   :..:...:|.:  |:...|.|...|.: .|.|.||.:.|||..:|.::
 Worm   203 AQNNHDHQYVESVRLLSEYAFEWILRPW--LRLKPLWYLTGPGH-EYDRHLKIVTDFTKTVIKEK 264

  Fly   255 IEA----HKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSG 315
            .|.    |....|.|:      ::.|||||.||....:|. :|..::.|||.||||||||||::.
 Worm   265 WEEFQKFHVDPVVKTD------KRSMAFLDLLLELRNEGL-MNEDDIREEVDTFMFEGHDTTSAS 322

  Fly   316 VSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGR 380
            :.:.::.|:.:.:.|.|:.:|...:.|.|:  ||.|..::.|||||:..:||:.|:||||||.||
 Worm   323 MGWTLWCLAHNPEFQEKVIQEVDGIFGTSD--RDCTNDDLKQMKYLEKCLKESLRMYPSVPFFGR 385

  Fly   381 FTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG---PFEYVPFSAGPR 442
            ..|:|.||:||..|||..:.:..::|..|..:|.:|:::.||.|..:|.|   .:..:|||||||
 Worm   386 TVEQDVVINGDFFPKGVRIIVMPLLLQRNPLIFDNPNQYNPENFSEDKIGSRHAYSDIPFSAGPR 450

  Fly   443 NCIGQKFALLEIKTVVSKIIRNFEVLPA--------LDELVSKDGYISTTIGLP 488
            ||||||||::|.|.|:|...|.:.|..:        |.||:.|     :::|.|
 Worm   451 NCIGQKFAMMEEKAVISWFFRKYRVTASQPFGMNKILPELILK-----SSLGFP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	167/448 (37%)
cyp-37B1	NP_507109.1	p450	41..475	CDD:278495	166/446 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28797
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890