Protein Alignment Cyp4e2 and cyp-37A1

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_496939.2
• Gene: cyp-37A1 / 175053
• WormBaseID: WBGene00008499
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 500
• Identity: 178/500 - (35%)
• Similarity: 269/500 - (53%)
• Gaps: 45/500 - (9%)

  Fly     4 VLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQY-- 66
            |:|:...|..:|....|  ..|...:::|.:||..|||:|...|...:|.|....:::|..:|
 Worm    12 VIYVVFNLSKILKFVKE--RMRLYHLMSKIDGPLALPLLGTTFQFKMDPVEFALQLYNWGLEYST 74

  Fly    67 -GKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKM 130
             |.....||:|.|..|:|.:.:..:.:|.|..||.||..|.:..||||.|||.::|.||...|||
 Worm    75 KGSSLAAFWMGPYPMVIVLTPEANKKVLESNALINKSSEYDIFLPWLGTGLLLASGEKWRGRRKM 139

  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIKHLKTVA--AGDNIFDFQEQAHYLTLDVICDTAMGVSINA 193
            :||:||||:|.||..|.|..|...::.::..|  ..|:..|.........||:||:||||.:::|
 Worm   140 MTPSFHFNVLIDFQVVFNSQSMILLEQIENAAKKTDDSTIDAFPYIKRCALDIICETAMGTTVSA 204

  Fly   194 MENRSSSIVQAFKDMCYNINMRAFHPLKRNELLY----RLAPDYPA-YSRTLKTLQDFTNEIIAK 253
            ..|.:...|.|..:|    |..|| ..:|...|:    |....|.| :.|.|..:..||.::|.:
 Worm   205 QTNHTHPYVVAVNEM----NSLAF-KYQRMPWLWIKPIRQLIGYEADFQRNLDIVTSFTKKVIDR 264

  Fly   254 RIEAH--KSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGV 316
            ::..|  ..|.|..    |...||.||||.|:....:| .|..:::.|||.||||||||||::|:
 Worm   265 KLREHDETDGMVVV----EEESKKKAFLDMLIEKKEEG-GLGYEDIREEVDTFMFEGHDTTSAGI 324

  Fly   317 SFAVYLLSRHQDEQRKLFKEQREVM-GNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGR 380
            .::::.|:...:.|:|..:|..|:. |.|   |:.:.:::.:||||:..:|||.|:.||||.:.|
 Worm   325 GWSLWCLANCPEYQKKCHEELDEIFEGTS---RECSVEDLKKMKYLEKCVKEALRMRPSVPQMAR 386

  Fly   381 FTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF---ELEKPGPFEYVPFSAGPR 442
            ..|::..|||.::|||.::.:....:..|.:.|.:...|.||||   |:.|...:.|:|||||||
 Worm   387 SVEEEVEIDGKILPKGCSVMISPAFIQNNPRTFPNHEVFDPERFNEDEISKRHAYAYIPFSAGPR 451

  Fly   443 NCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGL 487
            ||||||||:.|.|||:|.::|.|              :|.|.|||
 Worm   452 NCIGQKFAMQEEKTVISWVLRRF--------------HIHTDIGL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	158/432 (37%)
cyp-37A1	NP_496939.2	CYP4	78..501	CDD:410721	158/431 (37%)