DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4e2 and cyp-31A5

DIOPT Version :9

Sequence 1:	NP_001286196.1	Gene:	Cyp4e2 / 35822	FlyBaseID:	FBgn0014469	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001343697.1	Gene:	cyp-31A5 / 13198891	WormBaseID:	WBGene00013381	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	258	Identity:	81/258 - (31%)
Similarity:	128/258 - (49%)	Gaps:	1/258 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWWHQ 65
            |..::...|.....::|:|.....|.|:||...|.||..|::|:......:|...::.|....:.
Worm     1 MGVIIPAVLLASATVIAWLIYKHLRMRQVLKHLNQPRSYPIVGHGLITKPDPEGFMNQVIGMGYL 65

  Fly    66 YGKDNF-VFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRK 129
            |..... :.|||.:..:::.|:..:|.|.||...:.|...|.|..||||:.:|||...:|...||
Worm    66 YPDPRMCLLWIGPFPCLMLYSADLVEPIFSSTKHLNKGFAYVLLEPWLGISILTSQKEQWRPKRK 130

  Fly   130 MITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSINAM 194
            ::||.||::||:||..:.||.|...|:.|..:...|...|........|||:||:|:||.:|.|.
Worm   131 LLTPTFHYDILKDFLPIFNEQSKILIQKLCCLGVADEEVDVLSVITLCTLDIICETSMGKAIGAQ 195

  Fly   195 ENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEA 257
            ...::..|.|...:...|:.|..:||..|..:|.|..|...:.:.|..|.|||.::|.:|.||
Worm   196 LAENNEYVWAVHTINKLISKRTNNPLMWNSFIYNLTEDGRTHEKCLHILHDFTKKVIVERKEA 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	72/224 (32%)
cyp-31A5	NP_001343697.1	p450	36..>261	CDD:325183	72/223 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750