Protein Alignment Cyp4e2 and LOC1280195

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_061512680.1
• Gene: LOC1280195 / 1280195
• VectorBaseID: AGAMI1_003043
• Length: 519
• Species: Anopheles gambiae
• Alignment Length: 521
• Identity: 186/521 - (35%)
• Similarity: 287/521 - (55%)
• Gaps: 67/521 - (12%)

  Fly     4 VLYIFLALPLL--LVAYLELSTFRRRRVLNKFNGPRGLPLMGNAHQM-GKNPSEILDTVFSWWHQ 65
            ||.:.|..|:|  |:..:::|     ::.:|..||:..|.:|..:.: ||...||...:.....|
Mosquito    15 VLVLLLLTPVLQWLIRRVQMS-----QIYDKIPGPKAYPFVGTLYLLFGKKSHEIFTLIDQRTRQ 74

  Fly    66 YGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHKHRKM 130
            |...:.: |:|....|.::.::|:|.|:.:.....|:.:|:....|||.|||||.|.:|.:|||:
Mosquito    75 YDGIHRI-WVGMTPEVRLSRAEYVEQIIGASKHTEKATMYRFLGDWLGEGLLTSKGERWFQHRKL 138

  Fly   131 ITPAFHFNILQDFHEVMNENSTKFIKHLKTVA-AGD--NIFDFQEQAHYLTLDVICDTAMGVSIN 192
            |||.||||||..|.||..||....::.|:..| .|.  ||:.:..:|   .|||||:|||||.::
Mosquito   139 ITPTFHFNILDGFCEVFAENGAVLVERLQRHANTGQPVNIYPYVTKA---ALDVICETAMGVQVH 200

  Fly   193 AMENRSSSIVQAFKDMCYNIN-------MRAF-HP---LKRNELLYRLAPDYPAYSRTLKTLQDF 246
            |   :::....|:.:..|.::       :|.: ||   .:|:.|.:|.|       :.|..|..:
Mosquito   201 A---QTAGEDNAYVNAVYELSSLFLERLVRPWLHPDWTFRRSALGHRQA-------QLLAILHGY 255

  Fly   247 TNEIIAKRI---------EAHKSGAVSTNAGDEFTRKKMAFLDTLLSS--TIDGRP-LNSKELYE 299
            |.::|.:|.         |.::..|.....|   .||::||||.||.|  |..|.| |..:::.|
Mosquito   256 TRKVIQERRRTLDQQHAGERNQPEAEGDGLG---RRKRLAFLDLLLQSATTGTGSPLLTDEDVRE 317

  Fly   300 EVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLF 364
            ||.|||||||||||:|:|:|::||:.|.:.|.::.:|...:.|.|:  |.||.|:::.|:.|:..
Mosquito   318 EVDTFMFEGHDTTTAGMSWALFLLALHPEVQERVHQEIDSIFGGSD--RPATMQDLTAMRLLERC 380

  Fly   365 IKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKP 429
            :||..|:||||.|.||.|.:|..:.|..||.||.:.:....:..:|:.|.|...|.|:||..|:.
Mosquito   381 LKETLRLYPSVAFFGRTTSEDVTLGGYHVPAGTIVGIHAYNVHRDERFFPDAETFDPDRFLPERT 445

  Fly   430 G----PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLP--------ALDELVS--KDGY 480
            .    |:.|:||||||||||||||||||.|.:||.|:|.|.:..        .::||::  |||.
Mosquito   446 AENRHPYAYIPFSAGPRNCIGQKFALLEEKCLVSSILRRFRIRSHRTRAEQLIVNELITRPKDGI 510

  Fly   481 I 481
            :
Mosquito   511 L 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	168/454 (37%)
LOC1280195	XP_061512680.1	None