Protein Alignment Cyp4e2 and LOC1273546

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_001237478.4
• Gene: LOC1273546 / 1273546
• VectorBaseID: AGAMI1_006380
• Length: 494
• Species: Anopheles gambiae
• Alignment Length: 532
• Identity: 169/532 - (31%)
• Similarity: 272/532 - (51%)
• Gaps: 54/532 - (10%)

  Fly     5 LYIFLALPLLLVAYLELSTFRRR--RVLNKFNGPRGLPLMGNAHQMGKNPSEI-LDTVFSWWHQY 66
            :.:::.|..|.|..|....||.:  |.:....||....|:||..::.:..::: .:.:|.::.:|
Mosquito     1 MIVYVLLIALCVLVLRFVAFRYKVYRTVGHLPGPPVNFLLGNTLELVRYDTQVFFEKLFEYFQRY 65

  Fly    67 G------KDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWH 125
            |      ..|.| ||      :.:|...:|.|:||.....||..|.:...|||.|:|...|:.|.
Mosquito    66 GTIVRLDMINKV-WI------IFSSPHDIEQIISSNEFNRKSMDYDILQEWLGNGILLDYGNTWF 123

  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190
            .:|:.:|.||||.||..:..|..|.:...::  |.:.||....|........|||||.:|:|||.
Mosquito   124 SNRRALTGAFHFKILDTYVPVFEEQADVLVR--KLLDAGGATVDIFAMVKLYTLDVILETSMGVR 186

  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI 255
            ..| :...|..|:|..|:.:....|.::.:..::..:||...|..|.::|:..::||..:|.:|.
Mosquito   187 CRA-QLEDSDYVRAVTDLTHITFWRMYNAMGFSDWTFRLTKHYQTYRKSLQINREFTTSVITQRR 250

  Fly   256 EAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAV 320
            ....:..:|.....|  :.:::.||.||.|.|.||..:.:|:|.:|:.|||.|||||:|.::|.:
Mosquito   251 AELLAAGISDTTRPE--KGRLSLLDILLRSDITGRTFSDEEVYSQVNNFMFAGHDTTSSAITFIL 313

  Fly   321 YLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKD 385
            |..::|.:.|:::::   |::.....|...|.|.::.:|||:..|||:.|::|.||:..|..:.|
Mosquito   314 YACAKHPEVQQRVYE---EIVVELPDGEPVTQQRVNNLKYLEQVIKESLRMFPPVPYYSRHIDHD 375

  Fly   386 YVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFE--LEKPGPFEYVPFSAGPRNCIGQK 448
            ....|..:.||:|:.||..||.:|.:.|.:|.:||||||.  ..|..||.|:|||||.|||||||
Mosquito   376 TTQGGVRLEKGSTIVLGTYMLHHNPEYFPEPDQFRPERFADGETKRNPFAYIPFSAGSRNCIGQK 440

  Fly   449 FALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLK 513
            |||.|:||.:.||:|..:|                  .|||.:          :.|.:...|.||
Mosquito   441 FALNELKTALVKILRQCKV------------------ELPDPD----------FVPKMKMELVLK 477

  Fly   514 SENGLYIRLKER 525
            ..||:.:|..||
Mosquito   478 PVNGMQLRFLER 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	151/453 (33%)
LOC1273546	XP_001237478.4	None