Protein Alignment Cyp4e2 and LOC1272070

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_310940.6
• Gene: LOC1272070 / 1272070
• VectorBaseID: AGAMI1_004112
• Length: 552
• Species: Anopheles gambiae
• Alignment Length: 563
• Identity: 193/563 - (34%)
• Similarity: 290/563 - (51%)
• Gaps: 69/563 - (12%)

  Fly     3 FVLYIFLALPLLLVAYLELSTFRRRRV-----LNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSW 62
            |.|:..:.|.||......:..:.|||.     ::|..||.|||::||...:..:..||.:.:.:.
Mosquito    18 FTLFSPVTLLLLTTVSCAIYVYNRRRAHIVRHIDKIPGPAGLPILGNTLHINVDHDEIFNRIIAI 82

  Fly    63 WHQYGK-DNFV-FWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWH 125
            ...||: ..|. .|.|....|:::.:..:|.||.||..|.||..|:...||||.|||||.|.|||
Mosquito    83 RKLYGRIQGFSRAWNGPLPYVMISKASAVERILGSQKHIEKSHDYEFLKPWLGTGLLTSAGKKWH 147

  Fly   126 KHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVS 190
            ..||::||||||.||.||.::..|.|...:|.|:.....:..|:.........|||:|:||||..
Mosquito   148 PRRKILTPAFHFKILDDFVDIFQEQSAVLVKRLEAELGNEQGFNCFPYVTLCALDVVCETAMGRQ 212

  Fly   191 INAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRI 255
            :||..|..|..|:|...:...:..|......:.:.:::|..||..:.:.|..|.:|:|.:|.:|.
Mosquito   213 VNAQCNSDSDYVKAVYQIGSIVQNRQQKIWLQPDFIFKLTQDYKNHQKCLAILHEFSNRVIHERK 277

  Fly   256 EAHK------------------SGAVST-----NAGDEF-------TRKKMAFLDTLLSSTIDGR 290
            |..:                  .||..|     |..|::       .:|::||||.|:.::.||.
Mosquito   278 EEIRRQKQQLGDKNNNNNNNGGGGAAGTDQDGNNNKDDYLSHEELGRKKRLAFLDLLIEASQDGA 342

  Fly   291 PLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEI 355
            .|:.:::.|||.||||||||||::.:|:.:.||......|.::.:|..::|| .:..|..|.||:
Mosquito   343 VLSHEDIREEVDTFMFEGHDTTSAAISWILLLLGTEPTIQDRIVEEIDQIMG-GDRERFPTMQEL 406

  Fly   356 SQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFR 420
            ::||||:..|||..|:|||||.|.|...:|..|||.::|.|||..:.:..|..|.:||.:|.||.
Mosquito   407 NEMKYLEACIKEGLRLYPSVPLIARRLTEDVDIDGYVLPAGTTAMIVVYQLHRNPEVFPNPDKFN 471

  Fly   421 PERFELEK---PGPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYIS 482
            |:.|..|.   ..|:.|:|||||||||||||||:||.|:::|.::|.:.| .|:|
Mosquito   472 PDHFLPENCRGRHPYAYIPFSAGPRNCIGQKFAVLEEKSIISAVLRRYRV-EAVD---------- 525

  Fly   483 TTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525
                             .:.:..|...|.|:.:|||.||:..|
Mosquito   526 -----------------RRENLTLLGELILRPKNGLRIRIARR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	170/486 (35%)
LOC1272070	XP_310940.6	None