Protein Alignment Cyp4e2 and LOC1269350

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_061502575.1
• Gene: LOC1269350 / 1269350
• VectorBaseID: AGAMI1_001071
• Length: 495
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 136/548 - (24%)
• Similarity: 244/548 - (44%)
• Gaps: 80/548 - (14%)

  Fly     1 MWFVLYIFLALPLLLVAYLELSTFRRR-RVLNKFNGPRGLPLMGNAHQ-MGKNPSEILDTVFSWW 63
            :|.|..:..||.|..|..::...|... .|:..:     .|::|||.. :||:..::.:.:...:
Mosquito     4 LWLVALVLAALGLWQVWIVQRHRFASHLPVMQPY-----YPIIGNAQLFIGKSRVDLFNQLLQPF 63

  Fly    64 HQYGKDN-FVFWIGTYSNVLVTS-SKYLEFILSSQTLITKS---DIYQLTHPWLGLGLLTSTGSK 123
            .||  |. |..|:|. ..||.|| ...:..:||....:.|.   |..:|.|     |:.......
Mosquito    64 RQY--DGWFKIWLGP-KLVLATSHPDIMNAVLSHPDCLEKPFFYDFVKLEH-----GIFAGHYHP 120

  Fly   124 WHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGD-----NIFDFQEQAHYLTLDVIC 183
            |...||.:.|.|:..||..|..|..:.:.:.::|::. :.||     :||.|..:.   ||:::|
Mosquito   121 WKTQRKALNPTFNTRILNSFIPVFVQCARQMVQHMEQ-SVGDVGRSISIFPFISKC---TLEMVC 181

  Fly   184 DTAMGVSINAMENRSSSIVQAFKDMCYNI----NMRAFHPLKRNELLYRLAPDYPAYSRTLKTLQ 244
            .|.:|..:.....:.:.|...  |.|:.:    .:...|.:   |||||.:.|....|....:..
Mosquito   182 GTTIGCDVMEQPGKETFIENV--DRCFELVAKRMLNIHHYI---ELLYRFSRDCIEESELRTSCY 241

  Fly   245 DFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGH 309
            .|...:|.|......|..:.....|  .:|.:.|.|.||::..:|.|....|:...:.:.:..|:
Mosquito   242 RFFETVIEKAKTRKNSTTIEHECED--YKKPLIFADQLLAAQHNGNPFTDIEVTHNIYSMIAAGN 304

  Fly   310 DTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPS 374
            |||...|:.....|:.|...|.::::|..:|..:.:  :|...:::.::.|::..|||:.|:.||
Mosquito   305 DTTALQVTHTCLFLAMHPAIQERVYREVMDVFPDPD--QDIEVEDLKKLTYMERVIKESLRLAPS 367

  Fly   375 VPFIGRFTEKDYVIDGDLVPKGTTLNLGLVML-------GYNEKVFKDPHKFRPERFELEKPGPF 432
            .|.|.|.|.||..|.|..:|:.:.:.:.:..:       |.:..:| ||.:|.|||.|......|
Mosquito   368 GPNIARQTMKDIEIAGVHIPRDSLIVMSIFSMHRRKDIWGPDADLF-DPDRFLPERSEGRSTNVF 431

  Fly   433 EYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDP 497
              :|||||.|||||.::|:|.:|.::|.|:|...:...|                      :.:.
Mosquito   432 --IPFSAGSRNCIGGRYAMLSMKVMLSSILRRLRLRSDL----------------------QMND 472

  Fly   498 YRHKYDPILSAVLTLKSENGLYIRLKER 525
            .:.::|      ||||.|:..::::::|
Mosquito   473 LQFRFD------LTLKLESEYFVQVEKR 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	119/472 (25%)
LOC1269350	XP_061502575.1	None