Protein Alignment Cyp4e2 and Cyp4v3

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 505
• Identity: 196/505 - (38%)
• Similarity: 273/505 - (54%)
• Gaps: 53/505 - (10%)

  Fly    37 RGLPLMGNAHQMGKNPSEILDTVFSWWHQYGKDNFV-FWIGTYSNVLVTSSKYLEFILSSQTLIT 100
            |..||:|:|..|..|.:|....:..:..::.....: .|||....|.:..::.:|.||:|...|.
Mouse    55 RAYPLVGHALYMKPNNAEFFQQLIYYTEEFRHLPIIKLWIGPVPLVALYKAENVEVILTSSKQID 119

  Fly   101 KSDIYQLTHPWLGLGLLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENS----TKFIKHLKTV 161
            ||.:|:...|||||||||||||||...|||:||.|||.||::|.:||||.:    .|..||:...
Mouse   120 KSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPTFHFTILENFLDVMNEQANILVNKLEKHVNQE 184

  Fly   162 AAGDNIFDFQEQAHYLT---LDVICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRN 223
            |.  |.|      .|:|   ||:||:||||.:|.|..|..|..|:....|...|..|...|....
Mouse   185 AF--NCF------FYITLCALDIICETAMGKNIGAQSNNDSEYVRTVYRMSDMIYRRMKMPWLWF 241

  Fly   224 ELLYRLAPDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGD---EFTRKKMAFLDTLLSS 285
            :|.|.:..:...:.|.||.|..|||.:||:|::..|:....|.||.   ....|:.||||.|||.
Mouse   242 DLWYLVFKEGRDHKRGLKCLHTFTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRKAFLDLLLSV 306

  Fly   286 T-IDGRPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRD 349
            | .:|..|:.:::.|||.||||||||||.:.:::::|||..:.:.|||:.:|..||.|.|.  |.
Mouse   307 TDEEGNRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSH--RP 369

  Fly   350 ATFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFK 414
            .|.:::.::||||..|||..||:||||...|...:|..:.|..|.|||...:....|..:.:.|.
Mouse   370 VTLEDLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGGYKVTKGTEAIIIPYALHRDPRYFP 434

  Fly   415 DPHKFRPERFELEKP---GPFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVS 476
            ||.:||||||..|..   .|:.|||||||||||||||||::|.||:::.|:|.|.|
Mouse   435 DPEEFRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQFWV--------- 490

  Fly   477 KDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLKERH 526
                         ...:||:...      |:..|.|:..||::|:||.||
Mouse   491 -------------ESNQKREELG------LAGDLILRPNNGIWIKLKRRH 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	184/446 (41%)
Cyp4v3	NP_598730.1	p450	51..517	CDD:278495	192/499 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844935
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.750