Protein Alignment Cyp4e2 and cyp4b1.6

DIOPT Version :10

• Sequence 1: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_002931495.3
• Gene: cyp4b1.6 / 100488386
• XenbaseID: XB-GENE-5864180
• Length: 519
• Species: Xenopus tropicalis
• Alignment Length: 545
• Identity: 173/545 - (31%)
• Similarity: 284/545 - (52%)
• Gaps: 90/545 - (16%)

  Fly    11 LPLLLVAY--LELSTFRRRRV--LNKFNGPRGLPLMGNAH---QMGKNPSEILDTVFSWWH--QY 66
            |.||||.|  .:|..:||:.|  .:.|.||:...|.||.:   |:||:    ||.|..|..  .|
 Frog    25 LCLLLVLYKAAQLYVWRRKLVAAFSPFPGPKCHWLYGNTYEFLQIGKD----LDLVLGWAQVFPY 85

  Fly    67 GKDNFVFWIGT-YSNVLVTSSKYLEFILSSQTLITKSDI-YQLTHPWLGLGLLTSTGSKWHKHRK 129
            |   ...|:|. |:.:::|...|.:.:|:.|.  .|.|: |:...||:|.|||..:|.||.:||:
 Frog    86 G---MPLWLGNFYATLIITHPDYAKAVLARQD--PKDDMAYKFIVPWIGEGLLVLSGPKWFQHRR 145

  Fly   130 MITPAFHFNILQ-------DFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHY---LTLDVICD 184
            ::||.||:::|:       |...||.:...|.:.:.|:|          |..||   :|||.|..
 Frog   146 LLTPGFHYDVLKPYVTLMSDCTRVMLDKWDKLMPNEKSV----------ELFHYVSLMTLDTIMK 200

  Fly   185 TAMGVSINAMENRSSSIVQAFKDMCYNINMR-AFHPLKRNELLYRLAPDYPAYSRTLKTLQDFTN 248
            .|...:.:...||.::.:.|..::.|.::.| .|.|. .|:|::.|:|....:.:.|.|....|:
 Frog   201 CAFSYNTSCQNNRDNAYINAVYELSYLVDQRFRFFPY-HNKLIFHLSPLGFRFRKALSTAHQHTD 264

  Fly   249 EIIAKRIEA--HKSGAVSTNAGDEFTRKK-MAFLDTLL-SSTIDGRPLNSKELYEEVSTFMFEGH 309
            ::|.:|.|:  |::..      |:..:|: :.|||.|| :...:|:.|:.::|..||.|||||||
 Frog   265 KVIKQRKESLMHETEL------DKIRQKRHLDFLDILLCAKDENGKGLSDEDLRAEVDTFMFEGH 323

  Fly   310 DTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSE-LGRDATFQEISQMKYLDLFIKEAQRVYP 373
            |||.||:|:.:|.::::.:.|:|..:|..|::|..| :|.|    ::.::.|..|.|||:.|:||
 Frog   324 DTTASGISWILYCIAKYPEHQQKCREEITELLGERETMGWD----DLGKIPYTTLCIKESLRLYP 384

  Fly   374 SVPFIGRFTEKDYVI-DGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG---PFEY 434
            .||.|||...|.... ||..:|:|.::.|.:..:..:..::|||..|.|.||..|...   |..:
 Frog   385 PVPGIGRRLSKPITFCDGRSLPEGASIILSIYSINRSPSLWKDPEVFDPLRFLPENSDNRHPHAF 449

  Fly   435 VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYR 499
            :||||||||||||.||:.|:|..|:..::.:|:.|.                 ||.|.:|
 Frog   450 LPFSAGPRNCIGQNFAMNEMKVAVALTLQRYELFPD-----------------PDNEPQK----- 492

  Fly   500 HKYDPILSAVLTLKSENGLYIRLKE 524
                   ...:.|:|.||::::|::
 Frog   493 -------VPQIVLRSLNGIHVKLRK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	147/473 (31%)
cyp4b1.6	XP_002931495.3	CYP4B-like	73..507	CDD:410771	153/488 (31%)