Protein Alignment Cyp4e2 and Cyp3a41b

DIOPT Version :9

• Sequence 1: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 511
• Identity: 118/511 - (23%)
• Similarity: 245/511 - (47%)
• Gaps: 73/511 - (14%)

  Fly     6 YIFLALPLLLVAYLELST---FRRRRVLNKFNGPRGLPLMGNAHQMGKNPSEILDTVFSWW---- 63
            ::.||:.|:|:......|   |:::.:    .||:.||.:|.          :|:.....|
Mouse    12 WVLLAIILVLLYRYGTRTHGLFKKQGI----PGPKPLPFLGT----------VLNYYKGLWKFDM 62

  Fly    64 ---HQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLT-----ST 120
               .:||| .:..:.|.....::|..:.::.:|..:..    .::.....:..:|:::     |.
Mouse    63 ECYEKYGK-TWGLFDGQMPLFVITDPEMIKNVLVKECF----SVFTNRREFGPVGIMSKAISISK 122

  Fly   121 GSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDT 185
            ..:|.::|.:::|.|....|::...|:.:.....:|:|...|........::.....::|||..|
Mouse   123 DEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITST 187

  Fly   186 AMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYR-LAPDYPAYS------RTLKTL 243
            :.||:::::.|.....|:..|.:   :.:..|.||..:.:|:. |.|.|...:      .:::..
Mouse   188 SFGVNVDSLNNPEDPFVEKAKGI---LRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSIEFF 249

  Fly   244 QDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDG------RPLNSKELYEEVS 302
            :.|.|.:...|:::.:             :.::.||..::::..:.      :.|:..|:..:..
Mouse   250 KKFVNRMKESRLDSKQ-------------KHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQSI 301

  Fly   303 TFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKE 367
            .|:|.|::||:|.:||.:|.|:.|.|.|:||.:|..|.:.|.   ...|:..:.:|:|||:.:.|
Mouse   302 VFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNK---APPTYDTVMEMEYLDMVLNE 363

  Fly   368 AQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERFELEKPG-- 430
            ..|:||....:.||.:||..::|..:|||:|:.:....|.::.:.:.:|.:|:||||..|..|
Mouse   364 TLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSI 428

  Fly   431 -PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELV----SKDGYI 481
             |:.|:||..|||||||.:||.:.:|..::|:::||...|..:..:    |:.|.:
Mouse   429 DPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLSRQGLL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	109/461 (24%)
Cyp3a41b	NP_001098629.1	p450	39..494	CDD:278495	112/480 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810