DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ad1 and CYP86A7

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_176558.1	Gene:	CYP86A7 / 842675	AraportID:	AT1G63710	Length:	523	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	133/565 - (23%)
Similarity:	236/565 - (41%)	Gaps:	118/565 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCRKYDFQ 71
            |.|:.|::|       .||.....:.....||..:|.||:|          |..:....|.:||.
plant     6 AAIILTLIV-------TYIIWFVSLRRSYKGPRVWPLVGSL----------PALITNAHRMHDFI 53

  Fly    72 G---------FRSLVF-------LQYHMMLS-DPAEIQNILSSSSLLYKE--HLYSFLRPWLGDG 117
            .         :::.:|       .|.|:.:: ||..:::||.:....|.:  ...|.....||||
plant    54 ADNLRMCGGTYQTCIFPIPFLAKKQGHVTVTCDPKNLEHILKTRFDNYPKGPSWQSVFHDLLGDG 118

  Fly   118 LLTSSGARWLKHQKLYAPAF-ERSAIEGYLRVVHRT-GGQFVQKLDVLSDTQEVFDAQELVAKCT 180
            :..|.|..|...:|..|..| .|:..:...|.|.|. ..:.|..|:......|..|.|:::.:.|
plant   119 IFNSDGDTWRFQRKTAALEFTTRTLRQAMARWVDRAIKNRLVPILESARSRAEPIDLQDVLLRLT 183

  Fly   181 LDIVCENATGQDSSSL------NGETSDLHGAIKDLCDVVQERTFSIVKRF---DALFRLTSYYM 236
            .|.:|....|:|..:|      ||......||           |.:.::||   :.::::..:..
plant   184 FDNICGLTFGKDPRTLSPEFPENGFAVAFDGA-----------TEATLQRFIMPEFIWKIRKWLR 237

  Fly   237 -----KQRRALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREII 296
                 ...|::|.:.:.|:.||:.|:.:|.       ||..::...|.||:     :.:|::|..
plant   238 LGLEDDMSRSISHVDNYLSEIINTRKLELL-------GQQQDESRHDDLLS-----RFMKKKESY 290

  Fly   297 EE------VSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIF----GENFAGEAD--- 348
            .:      ...||..|.|..:.|:|:..:.:|.:..:::|...|...|.    ..|.:...|
plant   291 SDKYLKYVALNFILAGRDTSSVAMSWFFWLVSLNPRVEEKIINEICTILIKTRDTNVSKWTDEPL 355

  Fly   349 -LARLDQMHYLELIIRETLRLYPSVP-----LIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNE 407
             ...:||:.||:..:.||||||||||     ::|    |.:..:||.|...:.|...:.::|..:
plant   356 TFDEIDQLVYLKAALSETLRLYPSVPEDSKFVVA----NDVLPDGTFVPSGSNVTYSIYSVGRMK 416

  Fly   408 KYFDDPC-TFRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPA 471
            ..:.:.| .|:|||:...:.:.....:|.|.|:||||.|:.:..|..|||::.:.:|.|..:..|
plant   417 FIWGEDCLEFKPERWLEESRDEKCNQYKFVAFNAGPRICLGKDLAYLQMKSITASILLRHRLTVA 481

  Fly   472 VDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
                 ||   |..|.           .:.:||..:.|:::.:.||
plant   482 -----PG---HRVEQ-----------KMSLTLFMKFGLKMDVHKR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	117/488 (24%)
CYP86A7	NP_176558.1	PLN03195	4..507	CDD:215627	131/563 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920