DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ad1 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	120/498 - (24%)
Similarity:	228/498 - (45%)	Gaps:	64/498 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LFQFGLKPAEYP-----KKVLQYCRKYDFQGFRSL--VFLQY------------HMMLSDPAEIQ 92
            :|.:.....:||     |..:|..|...|  |..|  :||.|            .:::|||:..:
plant   100 MFDWTGSDQDYPKVPEAKGSIQAVRNEAF--FIPLYELFLTYGGIFRLTFGPKSFLIVSDPSIAK 162

  Fly    93 NILSSSSLLYKEHLYSFLRPW-LGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQF 156
            :||..::..|.:.:.:.:..: :|.||:.:.|..|.:.::...||..:..:...:.:......:.
plant   163 HILKDNAKAYSKGILAEILDFVMGKGLIPADGEIWRRRRRAIVPALHQKYVAAMISLFGEASDRL 227

  Fly   157 VQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQE---RT 218
            .||||..:...|..:.:.|.::.||||:.:.....|..||..:|    |.|:.:..|::|   |:
plant   228 CQKLDAAALKGEEVEMESLFSRLTLDIIGKAVFNYDFDSLTNDT----GVIEAVYTVLREAEDRS 288

  Fly   219 FSIVKRFD-ALFRLTSYYMKQRR---ALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDV 279
            .|.:..:| .:::..|  .:||:   :|.|:...|:.:|:..:..:..|......:.:|:....:
plant   289 VSPIPVWDIPIWKDIS--PRQRKVATSLKLINDTLDDLIATCKRMVEEEELQFHEEYMNERDPSI 351

  Fly   280 LLTAKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFA 344
            |......|..:..:::.:::.|.:..||:..||.:::|.|.|:....:..|..||...:.|:.|.
plant   352 LHFLLASGDDVSSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVIGDRFP 416

  Fly   345 GEADLARLDQMHYLELIIRETLRLYPSVP-LIARTNRNPIDINGT-KVAKCTTVIMCLIAMGYNE 407
            ...|:.:|   .|...::.|:|||||..| ||.|:..|  ||.|. .:.:...:.:.:..:..:.
plant   417 TIQDMKKL---KYTTRVMNESLRLYPQPPVLIRRSIDN--DILGEYPIKRGEDIFISVWNLHRSP 476

  Fly   408 KYFDDPCTFRPERF--ENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRR--FEI 468
            .::||...|.|||:  :.|..|...:.|..:||..|||:||.:.||.::....::.|:||  |:|
plant   477 LHWDDAEKFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQI 541

  Fly   469 LPAVDGLPP-----GINDHSREDCVPQSEYDPVLNIRVTLKSE 506
            .|   |.||     |...|:.|.          |.:.||.:::
plant   542 AP---GAPPVKMTTGATIHTTEG----------LKLTVTKRTK 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	110/455 (24%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	120/498 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.920