DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ad1 and CYP96A9

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_195658.3	Gene:	CYP96A9 / 830103	AraportID:	AT4G39480	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	127/561 - (22%)
Similarity:	247/561 - (44%)	Gaps:	100/561 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LIAIAIILATILVFKGVRIF--------NYIDHMAGIMEMIPG-----PTPYPFVGNLFQFGLKP 54
            |:.|:|.....|:|   |||        :::.:.. ::.|:||     |..|.|:..:.:.|
plant     6 LLEISIAFFCFLIF---RIFLISKKPHRSFLTNWP-LLGMLPGLLTVLPRVYDFITEVLEDG--- 63

  Fly    55 AEYPKKVLQYCRKYDFQGFRSLVFLQYHMMLSDPAEIQNILSSSSLLY-KEHLYSFLRPWLGDGL 118
                  .|.|.....|.|...::|      ..|||.|.:|:||:...| |...:..|...||||:
plant    64 ------NLNYLFIGPFLGGIDMLF------TVDPANIHHIMSSNFANYPKGTEFKKLFDVLGDGI 116

  Fly   119 LTSSGARWLKHQK-----LYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAK 178
            ..:....|...:|     :..|.|:|.::...|..:.:   ..|..||.::..:.|.|.|::..:
plant   117 FNADSDLWKDLRKSSQSMMNHPDFQRFSLATSLSKLEK---GLVPLLDHVAKEKLVVDLQDVFQR 178

  Fly   179 CTLDIVCENATGQDSSSLNGETSDLH--GAIKDLCDVVQERTF--SIVKRFDALFRLTSYYMKQR 239
            .|.|.....|||.|...|:.|..::.  .|:.|..:.:..|.|  .:|.:...|..:.: .:|.:
plant   179 FTFDTTFVLATGYDPGCLSVEMPEIEFARALDDAEEAIFYRHFKPEVVWKMQRLIGVGA-ELKLK 242

  Fly   240 RALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLK--------EREII 296
            ||.::.....::.|:.:|.:::        |.|:......||.:.::....|        :|.:.
plant   243 RAHAIFDRVCSKCIASKRDEIS--------QGIDSSSSKDLLMSSINVDTTKYKLLNPSDDRFLR 299

  Fly   297 EEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEE-QRRIFGENFAGEADLA---------R 351
            :.:.:|:..|.|...:|:::..:.|..:.|...|..:| ...:|..|...:..::         .
plant   300 DTILSFMLAGRDTTGSALTWFFWLLCNNQEAMTKIRQEINTNLFPRNKTDDGSVSYDSDSFNPQE 364

  Fly   352 LDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI--NGTKVAKCTTVIMCLIAMGYNEKYF-DDP 413
            :.::.||...:.|.|||||.||...::...| |:  :|.||...:.::.||.::|..:..: :|.
plant   365 VKKLVYLHGAVCEALRLYPPVPFNHKSPAKP-DVLPSGHKVKANSRILFCLYSLGRMKSVWGEDA 428

  Fly   414 CTFRPERFENPTG-NVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDG--L 475
            ..|:|||:.:.:| :|...::|.:.|:||||.|:.::.||.|||.:..::::.::| ..|:|  :
plant   429 MEFKPERWISESGRSVHEPSYKFLSFNAGPRTCLGKEVAMTQMKTVAVKIIQNYDI-NVVEGHKI 492

  Fly   476 PPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
            .|..:                    |.|..::|:::.:.||
plant   493 KPAPS--------------------VILHMKHGLKVTVSKR 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	110/470 (23%)
CYP96A9	NP_195658.3	p450	1..513	CDD:386267	125/559 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010