DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ad1 and CYP86C2

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_189243.1	Gene:	CYP86C2 / 822212	AraportID:	AT3G26125	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	114/488 - (23%)
Similarity:	206/488 - (42%)	Gaps:	98/488 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 YHMMLSDPAEIQNILSSS------SLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQK-----LYA 134
            |..|.|.||.|:.:|.::      ...|||.    .|..|.||:..:....|.:.::     :::
plant    91 YGAMTSVPANIEYMLKTNFKNFPKGEFYKER----FRDLLEDGIFNADDESWKEQRRIIITEMHS 151

  Fly   135 PAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGE 199
            ..|...:.:....::.|   :.::.::..|.:||.||.||::.:.|.|.:|....|.|..:|:.:
plant   152 TRFVDHSFQTTRDLIER---KLLKVMESFSKSQEAFDLQEILLRLTFDNICIAGLGDDPGTLDDD 213

  Fly   200 TSDLHGAIKDLCDVVQERTFSIVKRF--------DALFRLTSYYMKQRRALSLLRSELNRIISQR 256
            ...:     ......:|.|.|.:.||        ...|....|....|.|:..:.:.:::::.:|
plant   214 LPHV-----PFAKAFEEATESTLFRFMIPPFVWKPMKFFDIGYEKGLREAVETVHNFIDKMVVER 273

  Fly   257 RHQLAAENTCQQGQPINKPFLDVL-----------------LTAKLDGKVLKEREIIEEVSTFIF 304
            ...|..:.|....:.      |||                 .|||.         ..:..::||.
plant   274 IAMLKDQGTLANSKS------DVLSRLIQIESHKRGDENDRFTAKF---------FRQFCTSFIL 323

  Fly   305 TGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGE--------NFAGEADLAR------LDQM 355
            .|.|..:.|:::..:.:::|.|::.|...|.|.|..:        :..||.:.:|      |:.|
plant   324 AGRDTSSVALTWFFWLITKHPEVETKILHEIREILNQREKNKYKLDETGEKESSRHFTVKELNDM 388

  Fly   356 HYLELIIRETLRLYPSVPL-IARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPC-TFRP 418
            .||:..:.|:|||||.:|: :.:.....:..:||.:.|.:.|...:.|||..|..:...| .|:|
plant   389 VYLQAALSESLRLYPPIPMEMKQATEEDVFPDGTFLRKGSRVYFSVYAMGRMESIWGKDCEMFKP 453

  Fly   419 ERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHS 483
            ||:......|..:.||.|.|:||||.|:.:.||..|||.:.:.:|..:.|  .||      .||.
plant   454 ERWIQGGQYVSDDQFKYVVFNAGPRLCLGKTFAYLQMKMVAASILLNYSI--KVD------QDHV 510

  Fly   484 REDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
               .||:        :..||..::|:::|:..|
plant   511 ---VVPR--------VTTTLYMKHGLKVRITPR 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	103/440 (23%)
CYP86C2	NP_189243.1	PLN03195	42..533	CDD:215627	114/488 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910