DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ad1 and CYP704A2

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_182075.1	Gene:	CYP704A2 / 819159	AraportID:	AT2G45510	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	129/524 - (24%)
Similarity:	227/524 - (43%)	Gaps:	111/524 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LIAIAIILATIL-------VFKGVRIF--------NYIDHMAGIMEMIPGPTPYPFVGNLFQFGL 52
            |.:|||.:||.:       ::..:|||        .|....|.:.::            ||...
plant     4 LTSIAITVATTIFIVLCFTIYLMIRIFTGKSRNDKRYAPVHATVFDL------------LFHSD- 55

  Fly    53 KPAEYPKKVLQYCRKYDFQ--------GFRSLVFLQYHMMLSDPAEIQNILSSSSLLY------K 103
                         ..||::        .:|.|...|..::.:||..:::||.:....|      :
plant    56 -------------ELYDYETEIAREKPTYRFLSPGQSEILTADPRNVEHILKTRFDNYSKGHSSR 107

  Fly   104 EHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGY-LRVVHRTGGQFVQKLDVLSDTQ 167
            |::...    ||.|:....|.:|.:.:||.:..|....:..: ..|..|...:.|..:...:.:.
plant   108 ENMADL----LGHGIFAVDGEKWRQQRKLSSFEFSTRVLRDFSCSVFRRNASKLVGFVSEFALSG 168

  Fly   168 EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRF-DALFRL 231
            :.||||:|:.:||||.:.:...|.:...|:|.:.:  |  ::..:...|...:...|| |.|::|
plant   169 KAFDAQDLLMRCTLDSIFKVGFGVELKCLDGFSKE--G--QEFMEAFDEGNVATSSRFIDPLWKL 229

  Fly   232 TSYY-----MKQRRALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLK 291
            ..::     .|.:::::.:...:..:|:.:|.:||.|......:.|...|   |:.::.|.:.:.
plant   230 KWFFNIGSQSKLKKSIATIDKFVYSLITTKRKELAKEQNTVVREDILSRF---LVESEKDPENMN 291

  Fly   292 EREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRI------------FGENFA 344
            ::.:.:.:..|:..|.|..||.:|:.||.|.::..:|:|..:|.|.:            |.|:..
plant   292 DKYLRDIILNFMIAGKDTTAALLSWFLYMLCKNPLVQEKIVQEIRDVTFSHEKTTDVNGFVESIN 356

  Fly   345 GEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDI--NGTKVAKCTTVIMCLIAMGYNE 407
            .||    ||:||||...:.|||||||.||:..|...|. |:  :|.:|:|...:.....||| ..
plant   357 EEA----LDEMHYLHAALSETLRLYPPVPVDMRCAEND-DVLPDGHRVSKGDNIYYIAYAMG-RM 415

  Fly   408 KYF--DDPCTFRPERF--------ENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQL 462
            .|.  .|...|:|||:        |:|        ||.:.|.||||.|:.:.||..|||.:...|
plant   416 TYIWGQDAEEFKPERWLKDGLFQPESP--------FKFISFHAGPRICLGKDFAYRQMKIVSMAL 472

  Fly   463 LRRF 466
            |..|
plant   473 LHFF 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	118/476 (25%)
CYP704A2	NP_182075.1	PLN03195	15..509	CDD:215627	123/513 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920