DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4ad1 and CYP96A1

DIOPT Version :9

Sequence 1:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_179899.1	Gene:	CYP96A1 / 816850	AraportID:	AT2G23180	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	568	Identity:	123/568 - (21%)
Similarity:	252/568 - (44%)	Gaps:	108/568 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFLIAIAIILATILVFK---GVRIFNYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPAEYPKKVL 62
            |.||.:..:..::|.|.   |..:.:...|.:.:       |.:||:|.|          |..::
plant     1 MALITLLEVSISLLFFSFLYGYFLISKKPHRSFL-------TNWPFLGML----------PGLLV 48

  Fly    63 QYCRKYDF-----------QGFRSLVFLQYHMMLS-DPAEIQNILSSSSLLY-KEHLYSFLRPWL 114
            :..|.|||           ..|:...|....|::: |||.|.:|:||:...| |...:..:...|
plant    49 EIPRVYDFVTELLEASNLTYPFKGPCFGGLDMLITVDPANIHHIMSSNFANYPKGTEFKKIFDVL 113

  Fly   115 GDGLLTSSGARW----------LKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEV 169
            |||:..:....|          :.||.     |:|..:.   .::.:.....|..||.:::.::|
plant   114 GDGIFNADSELWKDLRKSAQSMMTHQD-----FQRFTLR---TIMSKLEKGLVPLLDYVAEKKQV 170

  Fly   170 FDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLCDVVQERTFSIVKRFDALFRLTSY 234
            .|.|::..:.|.|.....|||.|...|:.|...:..|  ...|..:|..|....:.:.::::..:
plant   171 VDLQDVFQRFTFDTSFVLATGVDPGCLSTEMPQIEFA--RALDEAEEAIFFRHVKPEIVWKMQRF 233

  Fly   235 Y-----MKQRRALSLLRSELNRIISQRRHQL--AAENTCQQGQPINKPFLDV----------LLT 282
            .     :|.::|.|......::.|:.:|.::  ...|.....:.:...:::|          ||.
plant   234 IGFGDELKMKKAHSTFDRVCSKCIASKRDEITNGVINIDSSSKDLLMCYMNVDTICHTTKYKLLN 298

  Fly   283 AKLDGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEE------QRRIFGE 341
            .. |.|.|::.     :.:|:..|.|..::|:::..:.||::.:...|..:|      .|....:
plant   299 PS-DDKFLRDM-----ILSFMLAGRDTTSSALTWFFWLLSKNPKAITKIRQEINTQLSPRTNDFD 357

  Fly   342 NFAGEADLARLDQMHYLELIIRETLRLYPSVPLIART-NRNPIDINGTKVAKCTTVIMCLIAMGY 405
            :|..:    .|:::.|:...:.|.|||||.||...:: .::.:..:|.:|...:.::.||.::|.
plant   358 SFNAQ----ELNKLVYVHGALCEALRLYPPVPFQHKSPTKSDVLPSGHRVDASSKIVFCLYSLGR 418

  Fly   406 NEKYF-DDPCTFRPERFENPTGN-VGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEI 468
            .:..: :|...|:|||:.:.:|. :.:.:||.:.|:||||.|:.::.||.|||.:..::::.:||
plant   419 MKSVWGEDASEFKPERWISESGRLIHVPSFKFLSFNAGPRTCLGKEVAMTQMKTVAVKIIQNYEI 483

  Fly   469 LPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQIRLRKR 516
             ..|:|                .:.:||.:|.:.:|  :|:::.:.||
plant   484 -KVVEG----------------HKIEPVPSIILHMK--HGLKVTVTKR 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	107/482 (22%)
CYP96A1	NP_179899.1	p450	1..512	CDD:299894	121/566 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920