Protein Alignment Cyp4ad1 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 547
• Identity: 139/547 - (25%)
• Similarity: 241/547 - (44%)
• Gaps: 96/547 - (17%)

  Fly     3 LIAIAIILATILVFKGVRIFNYIDHMAGIMEMIPGPTPYPFV------------GNLFQFGLKPA 55
            |:.:|:||...|:|.|     ||.::....:.||||....|.            .||..:
 Frog    12 LLLLALILICFLLFSG-----YIHYIHMKYDHIPGPPRDSFFLGHSPTMLRLMKNNLLMY----- 66

  Fly    56 EYPKKVLQYCRKYD----FQGFRSLVFLQYHMMLSDPAEIQNILSSSSLLYKEHLYSFLR----- 111
               ...|.:.:||.    ..|...::.|     :..|..::.:|.|.. ..|:..|..:.
 Frog    67 ---DHFLGWVQKYGPVVRINGLHRVIIL-----VVSPEAVKELLMSPK-YSKDKFYDVIANMFGV 122

  Fly   112 PWLGDGLLTSSG-ARWLKHQKLYAPAFERSAIEGYLRVVHRTGGQFVQKLDVLSDTQEVFDAQEL 175
            .::|.||:|... ..|.|.:::..|||.|:.:.|.:...:....:.::||...:|.:......::
 Frog   123 RFMGKGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDM 187

  Fly   176 VAKCTLDIVCENATGQDSSSLNGETSDLHGAIK-DLCDVVQERT----FSIVKRFDALFRLTSYY 235
            :::.|||::.:.|.|.:.:|||.:.:....||. .:..:|:.|.    :|:.||        .:.
 Frog   188 LSRLTLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVEMRNPMVRYSLAKR--------GFI 244

  Fly   236 MKQRRALSLLRSELNRIISQRRHQLAAENTCQQGQ--PINKPFLDVLLTAKLDGKVLKER---EI 295
            .|.:.::.|||......|.:|:.|:      |.|:  |::      :||..|.|..::|.   ||
 Frog   245 RKVQESIRLLRQTGKECIERRQKQI------QDGEEIPVD------ILTQILKGAAMEEECDPEI 297

  Fly   296 -IEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLE 359
             ::...||...|.:..|..:||.:..|.|:.||.:||..|...:.|..  .:.:...|.::.||.
 Frog   298 LLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSK--RDIEYEDLGKLQYLS 360

  Fly   360 LIIRETLRLYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCTFRPERFENP 424
            .:::|||||||:.|..:|.....:.|:|.||.:..|:::....||..|:|:.||.||.|:||...
 Frog   361 QVLKETLRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDRFSPD 425

  Fly   425 TGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVP 489
            ........|   |||.|||.||.:.|:..:.|.::::||:|:| ....:|....|.|..
 Frog   426 APKPYYSYF---PFSLGPRSCIGQVFSQMEAKVVMAKLLQRYE-FELAEGQSFKILDTG------ 480

  Fly   490 QSEYDPVLNIRVTLKSENGIQIRLRKR 516
                        ||:..:|:..|||.|
 Frog   481 ------------TLRPLDGVICRLRPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	119/466 (26%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	125/508 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910