Protein Alignment Cyp4ad1 and cyp19a1b

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_021326198.1
• Gene: cyp19a1b / 60640
• ZFINID: ZDB-GENE-001103-4
• Length: 513
• Species: Danio rerio
• Alignment Length: 510
• Identity: 121/510 - (23%)
• Similarity: 209/510 - (40%)
• Gaps: 106/510 - (20%)

  Fly     7 AIILATILVFKGVRIFNYIDHMAGI-----MEMIPGPTPYPFVGNLFQFGLKPAEYPKKVLQYCR 66
            |::..|:|:..|..:...:..:.|:     ...:|||.        :..||.|      ||.|.|
Zfish    14 AVVQGTLLLLTGTLMLILLHRIFGVKNWRNQSALPGPG--------WWLGLGP------VLSYSR 64

  Fly    67 ---------------KYD------FQGFRSLVFLQ------YHMMLSDPAEIQNILSSSSLLYKE 104
                           ||.      ..|..:::..:      ||::.|:  ......:|:..|...
Zfish    65 FLWMGIGTACNYYNEKYGSIARVWINGEETVILSKQVSSAVYHVLKSN--NYTGRFASAKGLQCI 127

  Fly   105 HLYSFLRPWLGDGLLTSSG-ARWLKHQKLYAPAFERSAIEGYLRV-VHRTGGQFVQKLDVLSDTQ 167
            .::.       .|::.:|. |:|.|.:..:..|.....::..:.| |..|..|    ||||   |
Zfish   128 GMFE-------QGIIFNSNIAKWKKVRTYFTKALTGPGLQKSVEVCVSATNRQ----LDVL---Q 178

  Fly   168 EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAI--------KDLCDVVQERTFS---- 220
            |..||...|     |::         :.|.....|:...:        |:|. :...|.||
Zfish   179 EFTDASGHV-----DVL---------NLLRCIVVDVSNRLFLRIPLNEKELL-IKIHRYFSTWQT 228

  Fly   221 IVKRFDALFRLTSYYMKQRRALSLLRSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKL 285
            ::.:.|..|:|...|.|...|...|:.|:.:::.|:|.  |..||.:..:   ..|...|:.|:
Zfish   229 VLIQPDIFFKLDFVYRKYHLAAKELQDEMGKLVEQKRQ--AINNTEKLDE---MDFATELIFAQ- 287

  Fly   286 DGKVLKEREIIEEVSTFIFTGHDPIAAAISFTLYTLSRHSEIQQKAAEEQRRIFGENFAGEADLA 350
            :...|...::.:.|...:....|.::.::.|.|..|.::|.::::..:|.:...|......|||.
Zfish   288 NHDELSVDDVRQCVLEMVIAAPDTLSISLFFMLLLLKQNSAVEEQIVQEIQSQIGSRDVESADLQ 352

  Fly   351 RLDQMHYLELIIRETLRLYPSVPLIARTNRNPIDINGTKVAKCTTVIMCLIAMGYNEKYFDDPCT 415
            :|   :.||..|:|:||.:|.|..|.|.:.....|:|.:|||.|.:|:.:..| :..::|..|..
Zfish   353 KL---NVLERFIKESLRYHPVVDFIMRQSLEDDYIDGYRVAKGTNLILNIGRM-HKTEFFKKPNE 413

  Fly   416 FRPERFENPTGNVGIEAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLRRFEILP 470
            |..|.|||   .|....|:  ||..|||.|:.:..||...||:|..:|.||.:.|
Zfish   414 FSLENFEN---TVPSRYFQ--PFGCGPRACVGKHIAMVMTKAILVTMLSRFTVCP 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	103/418 (25%)
cyp19a1b	XP_021326198.1	CYP19A1	72..486	CDD:410709	106/438 (24%)