Protein Alignment Cyp4ad1 and Cyp6a22

DIOPT Version :10

• Sequence 1: NP_610380.1
• Gene: Cyp4ad1 / 35821
• FlyBaseID: FBgn0033292
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 118/542 - (21%)
• Similarity: 204/542 - (37%)
• Gaps: 148/542 - (27%)

  Fly    23 NYIDHMAGIMEMIPGPTPYPFVGNLFQFGLKPA------EYPKKVLQYCRKYDFQGF--RSLVFL 79
            ::||.:..|.|...| ...||.|  |...|:|.      |..|::|    ..||..|  |.:
  Fly    51 HFIDIVTPIYEKFKG-NGAPFAG--FFMMLRPVVLVTDLELAKQIL----IQDFANFEDRGM--- 105

  Fly    80 QYHMMLSDPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEG 144
             ||....||             ...||:..            .|.:|...::..:|.|..:.::.
  Fly   106 -YHNERDDP-------------LTGHLFRI------------DGPKWRPLRQKMSPTFTSAKMKY 144

  Fly   145 YLRVVHRTGGQFVQKLDVLSDTQ--EVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAI 207
            ....|...|.:..|....|:|..  .:.:..:|:|:.|.|::...|.|.:.:.|....::.
  Fly   145 MFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEF---- 205

  Fly   208 KDLCDVVQERTFS----------IVKRFDALFR----------LTSYY-------MKQRRALSLL 245
                .::..|.||          .::.|..:.|          :|.:|       :|||....::
  Fly   206 ----AIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIV 266

  Fly   246 RSELNRIISQRRHQLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKEREIIEEVSTFIFTGHDPI 310
            ||:                           |:::|:..|..|::..| |:..:...|...|.|..
  Fly   267 RSD---------------------------FMNLLIEMKQRGELTIE-EMAAQAFIFFAAGFDTS 303

  Fly   311 AAAISFTLYTLSRHSEIQQKAAEE-QRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPL 374
            |:.:.|.||.|::...:|.|..|| .:.:...|  ||.....:.::.|:||:|.||||.||.:|.
  Fly   304 ASTLGFALYELAKQPALQAKLREEIDQALRLHN--GEFTYDSMQELRYMELVIAETLRKYPILPQ 366

  Fly   375 IARTNRNPIDINGTK---VAKCTTVIMCLIAMGYNEKYFDDPCTFRPERF------ENPTGNVGI 430
            :.|.:|:.....|.:   :.....:::.:..:.::...:.:|..|.||||      :.||.
  Fly   367 LTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTA---- 427

  Fly   431 EAFKSVPFSAGPRRCIAEKFAMYQMKALLSQLLR--RFEILPAVDGLPPGINDHSREDCVPQSEY 493
               ..:||..|||.||..:|...|....|..|||  .|.:.|..|               |:.|:
  Fly   428 ---AWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTD---------------PKIEF 474

  Fly   494 DPVLNIRVTLKSENGIQIRLRK 515
               |...:.|...|||.:::::
  Fly   475 ---LKSNILLCPANGIYLKVQQ 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ad1	NP_610380.1	CYP4	73..511	CDD:410721	102/480 (21%)
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	112/519 (22%)